Buenos Aires, Argentina
October 16, 2013
University of Buenos Aires, School of Law

A body of emerging evidence suggests that while not essential to life, flavonoids confer a range of effects that may support health and improve quality of life. In light of the consistent scientific and consumer interest in the role of these bioactive components, there is a need to consider a framework that could be applied to evaluate these components and enable evidence-based recommendations regarding their intake at levels that are safe, effective and benefit health. This session covered factors for consideration in making evidence-based dietary guidance possible, including:

  • An overview of a recent guidance document providing recommendations for designing, implementing and reporting clinical studies involving flavonoids.
  • A look at the type and level of evidence needed to support a public health recommendation, with particular emphasis on the link between flavonoids and vessel function and blood pressure.
  • The limitations in applying the current Dietary Reference Intake development process in the U.S. and elsewhere to flavonoids.
  • Elements that need to be considered in developing a path forward for dietary guidance involving flavonoids.

Speaker Presentations

Introduction: Handle with care: Flavonoids are different than essential nutrients
Doug Balentine, Unilever

Reporting requirements for flavonoid research: A critical component in enhancing our understanding
Mario Ferruzzi, Purdue University

Flavonoids: From data to databases to adequate intakes
Jeffrey Blumberg, Tufts University

Flavonoids and cardiovascular health – what progress has been made towards public health recommendations for flavonoids?
Carl L. Keen, University of California, Davis

The evolving path towards dietary guidance for flavonoids: Challenges, gaps, and priorities moving forward
John Erdman, University of Illinois

This session was supported by the IAFNS Technical Committee on Bioactives: Flavonoids, Polyphenols, and Carotenoids.