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Finalists Announced for the NUTRITION 2018 Dietary Bioactives Research Design Challenge

ResearchDesignChallenge

Non-essential bioactive dietary components hold promise for helping maintain optimal health and reducing risk of chronic disease, yet most efficacy studies are not sufficiently designed or powered to measure their safety. In the IAFNS Research Design Challenge at NUTRITION 2018, interdisciplinary teams pitched novel research designs that integrate safety measures and primary efficacy measures into a single study. Data obtained from such studies will improve the confidence of regulatory bodies with product oversight and health professionals providing advice to the general public.

Research Design Challenge Objective: Demonstrate proof of principle for novel research designs to integrate more safety measures in research with the primary purpose of testing efficacy of dietary bioactives.

Congratulations to the finalists of the IAFNS NUTRITION 2018 Research Design Challenge:

First Place:

Team Rutgers, led by Alexandra Kreitman, Department of Nutritional Sciences
"Measuring Safety and Efficacy of a Health Promoting Dietary Component: Monitoring GI Side Effects of a Putative α-Glucosidase Inhibitor."

Second Place: 

Team University of Alabama, Birmingham, led by Yuanyuan Rose Li, Department of Pharmacology and Toxicology
"An Effective Method to Balance Efficacy and Safety Test for Bioactive Soybean Isoflavone-Enhanced Chemotherapy in Breast Cancer Patients." Watch the Pitch Videos

This challenge session was supported by the IAFNS Bioactive Committee.

Design challenge judges were Paul Coates, Office of Dietary Supplements; James Coughlin, Coughlin & Associates; and Christina Khoo, Ocean Spray Cranberries. Research teams were mentored by Jiang Hu, Herbalife; and Tia Rains, Ajinomoto Health & Nutrition North America, Inc.

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Nutrition is the American Society for Nutrition's inaugural flagship meeting. IAFNS is supporting several sessions at Nutrition 2018:

Videos of the NUTRITION 2018 scientific sessions are now available! Click on a session to view the videos.

"The Future of Taste and Health - Converging Areas of Science to Promote Healthy Dietary Patterns" Expand

Saturday, June 9th, 2018. Supported by the IAFNS Taste and Diet Working Group.

Watch the full session

  • Lay of the Taste Land - Taste Evolution, Mechanisms, and Functions
    Gary Beauchamp, PhD, Monell Chemical Senses Center
  • Non-Mechanistic Determinants of the Taste Experience: How Culture, Environment, and Habit Influence Taste
    John Hayes, PhD, The Pennsylvania State University
  • Sensory Properties of Food and Implications for Food Choice
    Chris Simons, PhD, Ohio State University
  • Improving the Nutritional Profile of Products While Maintaining Taste: Industry Perspective
    Jane Leland, PhD, Consultant
  • Modifying Consumer Preference to Improve Dietary Choices
    Debra Zellner, PhD, Montclair State University
  • What Do We Know About Taste and Food Choice?
    Naomi Fukagawa, PhD, USDA ARS Beltsville Human Nutrition Research Center
"ASN/Canadian Nutrition Society Session: Ensuring Trust in Nutrition Science" Expand

Saturday, June 9th, 2018. Supported by the Scientific Integrity Consortium. IAFNS is an active member of the Consortium.

Watch the full session

  • Session Chair
    James House, PhD, University of Manitoba
  • Best Practices in Nutrition Science to Earn and Keep the Public's Trust
    Patrick Stover, PhD, Texas A&M
  • Report from the Scientific Integrity Consortium: Principles & Best Practices
    Catherine Woteki, PhD, Iowa State University
  • Using Risk of Bias Domains to Identify Opportunities for Improvement in Food- and Nutrition-related Research: An Evaluation of Research Type and Design, Year of Publication, and Source of Funding
    Esther Myers, PhD, RD, FADA, EF Myers Consulting, Inc. This talk was supported by the IAFNS Assembly on Scientific Integrity.
"Best Practices in Measuring and Reporting Blood Fatty Acids in Human Nutrition Studies" Expand

Monday, June 11th, 2018. Supported by the IAFNS Dietary Lipids Committee.

Watch the full session

  • Overview: The Need for Guidelines and the Process
    J. Thomas Brenna, PhD, University of Texas at Austin
  • Study Design and Interpretation
    Melanie Plourde, PhD, Université de Sherbrooke
  • Laboratory Analysis and Reporting
    Peter Jones, PhD, University of Manitoba
"The Sodium Conundrum" Expand

Tuesday, June 12th, 2018. Supported by the IAFNS Sodium Committee.

Watch the full session.

  • Introduction and Session Overview
    Moderator/Session Chair: Christine Taylor, PhD, FDA (retired)
  • Relationship of Sodium and Potassium to Chronic Disease: AHRQ Systematic Review
    Janet de Jesus, MS, RD, HHS, Office of Disease Prevention and Health Promotion
  • Developing Guidance for Inclusion of Chronic Disease Endpoints in DRIs: Implication for Sodium and Potassium
    Marian Neuhouser, PhD, RD, Fred Hutchinson Cancer Research Center
  • Overview of FDA Sodium Reduction Guidance
    Christine Taylor, PhD, FDA (retired)
  • Progress in Sodium Reduction by the Food Industry
    Joshua Anthony, PhD, MBA, The Campbell Soup Company
"Neurocognition: The First 1000 Days" Expand

This symposium aims to highlight recent scientific discoveries addressing how availability of distinct nutrients, along with genetic differences in nutrient metabolism capacity, affect the elaborate cellular and molecular processes that take place during brain development, focusing on basic science and clinically-­‐relevant scientific advances.

Symposium Chair:
Christopher Lynch, PhD, NIH, Director, Office of Nutrition Research
Chief, Nutrition Research Branch

Speakers:

Development of the Brain During the First 1000 Days of Life:
Lisa Freund, PhD, Eunice Kennedy Shriver National Institute Child Health and Human Development Iron: A Key Nutrient and a Paradigm of Nutrient-Brain Interactions:
Michael Georgieff, MD, University of Minnesota The Relation Between Maternal Genotype, Lipid Intake and Metabolism, and Infant and Toddler Cognitive Performance:
Carol Cheatham, PhD, UNC Chapel Hill Nutrition Research Institute The Impact of Maternal Choline Metabolism on Brain Development:
Steven Zeisel, MD, PhD, UNC Chapel Hill Nutrition Research Institute

 

 

More information about Nutrition 2018 is available here.

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Finalists Announced for the NUTRITION 2018 Dietary Bioactives Research Design Challenge

ResearchDesignChallenge

Non-essential bioactive dietary components hold promise for helping maintain optimal health and reducing risk of chronic disease, yet most efficacy studies are not sufficiently designed or powered to measure their safety. In the IAFNS Research Design Challenge at NUTRITION 2018, interdisciplinary teams pitched novel research designs that integrate safety measures and primary efficacy measures into a single study. Data obtained from such studies will improve the confidence of regulatory bodies with product oversight and health professionals providing advice to the general public.

Research Design Challenge Objective: Demonstrate proof of principle for novel research designs to integrate more safety measures in research with the primary purpose of testing efficacy of dietary bioactives.

Congratulations to the finalists of the IAFNS NUTRITION 2018 Research Design Challenge:

First Place:

Team Rutgers, led by Alexandra Kreitman, Department of Nutritional Sciences
"Measuring Safety and Efficacy of a Health Promoting Dietary Component: Monitoring GI Side Effects of a Putative α-Glucosidase Inhibitor."

Second Place: 

Team University of Alabama, Birmingham, led by Yuanyuan Rose Li, Department of Pharmacology and Toxicology
"An Effective Method to Balance Efficacy and Safety Test for Bioactive Soybean Isoflavone-Enhanced Chemotherapy in Breast Cancer Patients." Watch the Pitch Videos

This challenge session was supported by the IAFNS Bioactive Committee.

Design challenge judges were Paul Coates, Office of Dietary Supplements; James Coughlin, Coughlin & Associates; and Christina Khoo, Ocean Spray Cranberries. Research teams were mentored by Jiang Hu, Herbalife; and Tia Rains, Ajinomoto Health & Nutrition North America, Inc.

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