Conducting a Systematic Review for a Global Audience: Challenges in Merging Nutrition and Toxicological Evidence for a Safety Assessment of Caffeine
April 22, 2017
Chicago, Illinois, USA
Experimental Biology 2017
April 21, 2017 – April 25, 2017
Chicago, Illinois, USA
IAFNS supported various sessions at the 2017 Experimental Biology Conference.
Society of Toxicology Annual Meeting 2017 & Expo
March 12, 2017 – March 16, 2017
Baltimore, MD, USA
The Food and Chemical Safety Committee will be sponsoring multiple projects being presented at the SOT Annual Meeting.
Read more about Society of Toxicology Annual Meeting 2017 & Expo
Workshop: State of the Science on Alternatives to Animal Testing and Integration of Testing Strategies for Food Safety Assessments
February 28, 2017
College Park, MD, USA
- Harris Lieberman, US Army - Behavior - Video
- Charles O'Brien, University of Pennsylvania - Behavior - Video (See Lieberman for pdf)
- Jennifer Peck, PhD University of Oklahoma - Reproductive & Developmental Toxicity - Video
- Daniele Wikoff on behalf of Jeffrey Goldberger, University of Miami, Miller School of Medicine- Cardiovascular - Video
- Connie Weaver, PhD, Purdue University - Bone & Calcium - Video
- Milton Tenenbein, MD, University of Manitoba - Acute & Pharmacokinetics - Video
Moderated by Dennis Keefe, PhD
Panel includes: 6 of the 7 Scientific Advisory Board members, Daniele Wikoff of ToxStrategies (Scientific Review Team), Alison Kretser of IAFNS (Oversight Committee) Overall Conclusions - presented by Daniele Wikoff
Full session playlist
See IAFNS's other sessions at Experimental Biology 2017:
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8:30AM - 12:30PM
Ballroom S100BC
Speakers: Dennis Keefe, FDA; Harris Lieberman, USARIEM; Esther Myers, EF Myers Consulting; Charles O'Brien, University of Pennsylvania; Jennifer Peck, University of Oklahoma; Milton Tenenbein, University of Manitoba; Connie Weaver, Purdue University; Daniele Wikoff, ToxStrategies
Supported by the Caffeine Working Group
Session Info & Videos The Changing Brain: How Brain Plasticity, Exercise and Nutrition Affect Function and Cognition
Saturday, 22 April 2017
3:00PM - 5:00PM,
Ballroom S100BC
- Neurogensis and brain plasticity in the adult brain - Henriette van Praag, National Institute on Aging;
- The Relation of Exercise, fitness, & Adiposity to Cognitive and Brain Health - Charles Hillman, University of Illinois - Video
- Neuroinflammatory Processes in Cognitive Disorders - Sophie Laye, Universite Bordeaux - Video
- Exercise, Nutrition and Brain Funciton: What are the steps toward dietary and physical activity Recommendations? - Mary Ann Johnson, University of Georgia - Video
- Panel Discussion - Video
Sunday, 23 April 2017
8:30AM- 10:30AM
S105BCD
Speakers:
- Intro to Predictive Modeling: From Linear Regression Models to Mechanistic Mathematical Modeling - David Allison, University of Alabama at Birmingham - Video;
- Use of Predictive Modeling in the Design of Clinical Studies Kevin Hall, NIDDK - Video;
- Application of Predictive Modeling in Weight Loss Counseling - Corby Martin, Pennington Biomedical Research Center - Video;
- Application of Predictive Modeling in Personalized Nutrition - Ben van Ommen, TNO - Video;
- Utility of PRedictive Modeling for Public Health Obesity Policies - Emily Dhurandhar, Texas Tech University - Video;
- Summary and Wrap-Up - Diana Thomas, West Point - Video
Supported by the Protein Committee - Full session playlist
Tuesday, 25 April 2017
11:00AM - 12:30PM
S105AB
Speakers: Kara Livingston, Tufts University; Caleigh Sawicki, Tufts University
Supported by the Carbohydrate Committee Posters
Sources of dietary folate/folic acid in women of different races in the United States between 2009 and 2012: What is the role of fortified and enriched products?
Abstract Number: 6707
Poster Board Number C88
Presenter: Ray DeVirgiliis, George Washington University
Monday, 24 April
1:45PM-2:45PM [post_title] => Experimental Biology 2017 [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => experimental-biology-2017 [to_ping] => [pinged] => [post_modified] => 2023-01-23 04:48:49 [post_modified_gmt] => 2023-01-23 04:48:49 [post_content_filtered] => [post_parent] => 0 [guid] => https://iafnsconnect.wpengine.com/?post_type=event&p=2386 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 2203 [post_author] => 343 [post_date] => 2017-01-11 23:16:59 [post_date_gmt] => 2017-01-11 23:16:59 [post_content] => [post_title] => Society of Toxicology Annual Meeting 2017 & Expo [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => society-of-toxicology-annual-meeting-2017-expo [to_ping] => [pinged] => [post_modified] => 2017-06-23 13:26:01 [post_modified_gmt] => 2017-06-23 13:26:01 [post_content_filtered] => [post_parent] => 0 [guid] => https://iafnsconnect.wpengine.com/?post_type=event&p=2203 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 2252 [post_author] => 343 [post_date] => 2017-02-01 18:46:35 [post_date_gmt] => 2017-02-01 18:46:35 [post_content] =>
Co-hosted by U.S. Food and Drug Administration, Center for Food Safety & Applied Nutrition (CFSAN) and the IAFNS Technical Committee on Food & Chemical Safety
This workshop will bring together scientists from government, academia and industry to discuss the advances in testing strategies to reduce animal testing and the need for the development of a standardized approach for use of these alternative methodologies in food safety assessment.
Workshop Proceedings:
State of the Science on Alternatives to Animal Testing and Integration of Testing Strategies for Food Safety Assessments
Read the Proceedings Registration ExpandThere is no fee to attend the workshop but, registration is required by Tuesday, February 21. Please register for the workshop using this link: Workshop Registration
Webcast RegistrationRegister for webcast here: webcast registration
Webcast participants can submit questions online during the event. These will be answered as time allows. Agenda Expand
8:30-8:40 am: Welcome Suzanne Fitzpatrick, FDA Mansi Krishan, IAFNS
8:40-8:55amIntroductory Remarks
Dennis Keefe, FDA
Heidi Bialk, IAFNS Member Scientist 8:55-9:35am
Integrated Testing Strategies in Food Safety
Alan Boobis, Imperial College London [30 mins + 10 mins Q & A] 9:35-10:15am
State of the Science on High Through-Put Screening (HTS): Food Safety Perspective
Nadine Bewry, FDA 10:30-11:10am
Case Studies to Describe the Limitations of Using HTS data in Food Safety Assessment
Rebecca Clewell, ScitoVation 11:10 -11:50am
Identify and Translate Learnings from On-Going Assay Validation Efforts into Standard HTS Testing Practices
Richard Judson, EPA 12:50- 1:30pm
Read Across Approaches: Chemical Structure and Bioactivity Profiling Applicable to Food Safety
Grace Patlewicz, EPA 1:30-2:10pm
FDA Perspective on Read Across Approaches
Tim Adams, FDA 2:10-2:50 pm
Organ on a Chip Technology
Daniel Levner, Emulate 3:05- 4:30pm
Panel Discussion Moderator: Suzanne Fitzpatrick, FDA Panelists:
All speakers, Thomas Hartung, Johns Hopkins University and Katya Tsaioun, Johns Hopkins University 4:30-4:40pm
Concluding Remarks
Suzanne Fitzpatrick
FDA Mansi Krishan, IAFNS Videos Expand
A video of the workshop can be found on the FDA YouTube channel
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There continues to be interest within the scientific community in what is a safe level of caffeine intake and if certain populations should have modified recommendations. Since the 2003 release of the highly cited and valued review by Nawrot et al., "Effects of caffeine on human health", there have been more than 5,000 articles on the effects of caffeine in humans published, highlighting the need for an update to this body of work.
The Systematic Review of the effects of caffeine on human health took into account the challenges of including nutrition and toxicological evidence. The health endpoints reviewed for caffeine are: acute toxicity, behavior, bone and calcium homeostasis, cardiovascular health, developmental and reproductive toxicity, and pharmacokinetics in three healthy populations. The session will present the lessons learned and will emphasize the efforts taken to ensure transparency and rigor that allow for the achievement of a high level of scientific quality. Specific areas of focus will include challenges with identifying and integrating caffeine intakes by level of adversity (e.g., physiological or clinical endpoints), and difficulties in applying standard risk of bias tools across outcomes and endpoints.
Although this session will focus on the Caffeine Systematic Review as a case study, the process, findings, and lessons are relevant to nutrition researchers and professionals who utilize systematic reviews.
Agenda & Videos Expand WelcomeAlison Kretser, MS, RD, IAFNS The Caffeine Landscape - framing the need for the Systematic Review
Dennis Keefe, PhD, FDA
Video Striving for the Gold Standard in the Systematic Review Process
Esther Myers, PhD, RDN, FAND, EF Myers Consulting
Video The Methodology and Challenges of the Caffeine Systematic Review
Daniele Wikoff, PhD, ToxStrategies
Video Q&A
Moderated by Dennis Keefe, PhD
Video
10:10 - 10:25 Break
General Results of the Systematic ReviewDaniele Wikoff, PhD, ToxStrategies
Video
Results of Specific Health Endpoints- Scientific Advisory Board Members
- Harris Lieberman, US Army - Behavior - Video
- Charles O'Brien, University of Pennsylvania - Behavior - Video (See Lieberman for pdf)
- Jennifer Peck, PhD University of Oklahoma - Reproductive & Developmental Toxicity - Video
- Daniele Wikoff on behalf of Jeffrey Goldberger, University of Miami, Miller School of Medicine- Cardiovascular - Video
- Connie Weaver, PhD, Purdue University - Bone & Calcium - Video
- Milton Tenenbein, MD, University of Manitoba - Acute & Pharmacokinetics - Video
Moderated by Dennis Keefe, PhD
Panel includes: 6 of the 7 Scientific Advisory Board members, Daniele Wikoff of ToxStrategies (Scientific Review Team), Alison Kretser of IAFNS (Oversight Committee) Overall Conclusions - presented by Daniele Wikoff
Full session playlist
See IAFNS's other sessions at Experimental Biology 2017:
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Tech Summit: Innovative Tools for Assessing Diet & Physical Activity for Health Promotion
November 30, 2016 – December 1, 2016
La Jolla, CA, USA
This summit focused on questions including: How can the modifiable determinants of energy balance, physical activity, and dietary intake, be better measured in ways that support intervention?
FNCE 2016
October 15, 2016 – October 18, 2016
Boston, MA, USA
Dietary Sugar Intake: Systematic Review of Public Health Guidelines and their Recommendations
Compilation, Curation, and Prioritization of Food-Use Chemicals in ToxCast
September 29, 2016 – September 30, 2016
Durham, NC, USA
Read more about Compilation, Curation, and Prioritization of Food-Use Chemicals in ToxCast
Scientific Advances and Challenges in Safety Evaluation of Food Packaging Materials
September 27, 2016
Washington, D.C., USA
This workshop will provide a scientific forum to discuss the state of the science on toxicology, exposure and risk assessment as it relates to the safety of food packaging.
Read more about Scientific Advances and Challenges in Safety Evaluation of Food Packaging Materials
Food-Use Chemicals in ToxCast: Identification, Curation, and Evaluation
September 22, 2016
Durham, NC, USA
Dr. Agnes Karmaus (IAFNS 2012 Summer Fellow) has been invited to present at EPA’s Computational Toxicology Communities of Practice webinar series on the food-relevant chemicals in ToxCast. This work was supported by the IAFNS Technical Committee on Food and Chemical Safety.
Read more about Food-Use Chemicals in ToxCast: Identification, Curation, and Evaluation
- State of the Science of Energy Balance Research Across the Lifespan - David Allison, PhD, University of Alabama at Birmingham Video
- State of Technology and Innovation related to Physical Activity and Healthful Eating- Eric Hekler, PhD, Arizona State University Video
Additional Presentations
- Guidance and Standards for the Responsible Conduct of mHealth Research - Camille Nebeker, EdD, MS, UC San Diego Video
- Circadian Rhythm as it Relates to Overall Health, Wellness, and Risk for Disease - Satchin Panda, PhD, the Salk Institute Video
CHILDREN & YOUTH - Moderator: Tom Robinson, MD, Stanford
- Current Technologies in Diet Assessment & Intervention - Carol J. Boushey, PhD, MPH, RD, University of Hawaii Video
- Current Technologies in Physical Activity Assessment & Intervention - Jaqueline Kerr, PhD, MSc University of California San Diego Video
- Advances & Challenges in Measuring Dietary Intake and Physical Activity - Donna Spruijt-Metz, MFA, PhD, University of Southern California Video
Thursday, 1 December 2016
ADULTS - Moderators: Rick Troiano, PhD, NIH - Intro Video
- Current Technologies in Diet Assessment & Intervention - Rick Weiss, MS, Viocare Video
- Current Technologies in Physical Activity Assessment & Intervention - Anand Iyer, PhD, WellDoc Video
- Advances & Challenges in Measuring Dietary Intake and Physical Activity - Lauren Ptomey, PhD, RD, LD, University of Kansas Video
OLDER ADULTS - Moderators: David Klurfeld, PhD, USDA, & Tamara Harris, MD, National Institute on Aging - Intro Video
- Current Technologies in Diet Assessment & Intervention - Sai Das, PhD, Tufts University Video
- Current Technologies in Physical Activity Assessment & Intervention - Jacqueline Kerr, PhD, MSc, University of California San Diego Video
- Advances & Challenges in Measuring Dietary Intake and Physical Activity - Todd Manini, PhD, University of Florida Video
Concluding Panel & Summit Closing Remarks - Kevin Patrick, MD, MS, UCSD
Full event video playlist can be found on the IAFNS YouTube Channel.
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WelcomeMansi Krishan, IAFNS Introduction
Ron Osborn, IAFNS Member Scientist Challenges in Safety Assessment of Food Packaging Materials- Toxicology -
Jason Aungst, Division of Food Contact Notifications, U.S. FDA - Video Challenges in Safety Assessment of Food Packaging Materials - Chemistry
Kirk Arvidson, Division of Food Contact Notifications, U.S. FDA - Video Migration of Contaminant Residues from Food Packaging
Greg Pace, Sun Chemical Corporation - Video Analytical Methods for Evaluating Components of Food Packaging Materials
Tim Begley, U.S. FDA - Video Use of New/Improved Tools and Exposure Assessment Models for Food Packaging Materials
Cian O' Mahony, Crème Global - Video US Regulatory Perspective
Paul Honigfort, Division of Food Contact Notifications, U.S. FDA - Video Global Regulatory Perspective
Jim Huang, IAFNS Member Scientist - Video Panel Discussion - Video
Moderator: Ron Osborn, IAFNS Member Scientist
Panelists: Jason Aungst, Kirk Arvidson, Greg Pace, Tim Begley, Cian O'Mahony, Paul Honigfort
- In light of advancements in analytical methodologies which are allowing for progressively lower detection limits resulting in unexpected chemicals being detected in air, water, food, etc., how do we access and utilize this information for safety assessment of packaging materials?
- How do we evaluate the safety of nanomaterials in food packaging?
- In terms of assessing the safety of packaging materials, how much is enough?
Susan Selke, Michigan State University - Video Contaminant Residues in/from Recycled Paper-Paperboard and Plastics: Contaminant Identification, Food Safety Concerns and Regulatory Controls
Vanee Komolprasert, Division of Food Contact Notifications, U.S. FDA - Video Case Studies:
i. Mineral oil saturated hydrocarbons (MOSHs) and mineral oil aromatic hydrocarbons (MOAHs)
Stephen Klump, Nestle - Video ii. a) Di-isopropylnapthalene; and b) Poly- and perfluoroalkyl substances (PFASs)
Paul Honigfort, Division of Food Contact Notifications, U.S. FDA - Video Emerging Innovations and Technologies in Food Packaging
Young Kim, Virginia Tech University - Video Panel Discussion - Video
Moderator: Doug Copen, IAFNS Member Scientist
Panelists: Susan Selke, Vanee Komolprasert, Stephen Klump, Paul Honigfort, Jim Huang, Young Kim
- What are the challenges in utilizing recycled packaging materials in food contact applications and how do we address these challenges?
- What are the challenges in identification and safety evaluation of non-intentionally added substances (NIAS) in food contact materials? What are the potential approaches for considering NIAS in the risk assessment of food contact materials?
- The challenges of communicating scientific information to a nonscientific audience, particularly the importance of communicating the entire story (example- what we know, what we don't know, not just what we want them to know) while making the information as relevant as possible.
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This unique forum investigated current and emerging challenges related to improving energy balance behavior assessment and intervention via technology, and focused on how the research community might embrace and apply innovative new tools.
Am J Prev Med Theme Section: Innovative Tools for Assessing Diet and Physical Activity for Health Promotion
The Tech Summit resulted in four publications, appearing as a theme section in the American Journal of Preventive Medicine:
Advances and Controversies in Diet and Physical Activity Measurement in YouthThis report reviews current developments in dietary intake and physical activity assessment in youth.
Dietary Intake and Physical Activity Assessment: Current Tools, Techniques, and Technologies for Use in Adult PopulationsThis paper summarizes recent technological advancements, such as remote sensing devices, digital photography, and multisensor devices, which have the potential to improve the assessment of dietary intake and physical activity in free-living adults.
Diet and Activity Assessments and Interventions Using Technology in Older AdultsThis paper reports on the findings and recommendations specific to older adults from the “Tech Summit: Innovative Tools for Assessing Diet and Physical Activity for Health Promotion” forum organized by the North American branch of the International Life Sciences Institute.
Share Save Technology Innovations in Dietary Intake and Physical Activity Assessment: Challenges and Recommendations for Future DirectionsDietary intake (DI) and physical activity (PA) data are used in a variety of ways, including to determine nutrient adequacy and deficiency; to assess nutritional, fitness, and health status; to develop health promotion and behavioral interventions; and to understand food chemical and microbiological exposure, food–drug interactions, and pharmacokinetic effects. Methods used to capture these data must therefore be reliable and accurate to ensure confidence when determining quantitative DI and energy intake (EI), food behaviors, and energy expenditure (EE), especially for real-time monitoring and interventions. Moreover, because the underlying pathways and mechanisms regulating energy homeostasis are not fully understood, improved measures can help address challenges in understanding interrelationships between DI and PA.
Organized by:IAFNS Committee on Balancing Food & Activity for Health
University of California, San Diego
American College of Sports Medicine
with programmatic input from NIH and USDA ARS
Program
Wednesday, 30 November 2016
Welcome & Introductions - Video
IDENTIFY COMMON ISSUES - featured presentations
- State of the Science of Energy Balance Research Across the Lifespan - David Allison, PhD, University of Alabama at Birmingham Video
- State of Technology and Innovation related to Physical Activity and Healthful Eating- Eric Hekler, PhD, Arizona State University Video
Additional Presentations
- Guidance and Standards for the Responsible Conduct of mHealth Research - Camille Nebeker, EdD, MS, UC San Diego Video
- Circadian Rhythm as it Relates to Overall Health, Wellness, and Risk for Disease - Satchin Panda, PhD, the Salk Institute Video
CHILDREN & YOUTH - Moderator: Tom Robinson, MD, Stanford
- Current Technologies in Diet Assessment & Intervention - Carol J. Boushey, PhD, MPH, RD, University of Hawaii Video
- Current Technologies in Physical Activity Assessment & Intervention - Jaqueline Kerr, PhD, MSc University of California San Diego Video
- Advances & Challenges in Measuring Dietary Intake and Physical Activity - Donna Spruijt-Metz, MFA, PhD, University of Southern California Video
Thursday, 1 December 2016
ADULTS - Moderators: Rick Troiano, PhD, NIH - Intro Video
- Current Technologies in Diet Assessment & Intervention - Rick Weiss, MS, Viocare Video
- Current Technologies in Physical Activity Assessment & Intervention - Anand Iyer, PhD, WellDoc Video
- Advances & Challenges in Measuring Dietary Intake and Physical Activity - Lauren Ptomey, PhD, RD, LD, University of Kansas Video
OLDER ADULTS - Moderators: David Klurfeld, PhD, USDA, & Tamara Harris, MD, National Institute on Aging - Intro Video
- Current Technologies in Diet Assessment & Intervention - Sai Das, PhD, Tufts University Video
- Current Technologies in Physical Activity Assessment & Intervention - Jacqueline Kerr, PhD, MSc, University of California San Diego Video
- Advances & Challenges in Measuring Dietary Intake and Physical Activity - Todd Manini, PhD, University of Florida Video
Concluding Panel & Summit Closing Remarks - Kevin Patrick, MD, MS, UCSD
Full event video playlist can be found on the IAFNS YouTube Channel.
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