IAFNS 2026 Science Briefs

Food Classification

Ultra-Processed Food Intake and Cognitive Decline in Older Adults

Global ultra-processed foods (UPFs) intake has increased. While several studies have linked the intake of specific UPF products to cognitive decline, fewer have investigated overall dietary UPF intake, with conflicting results.

IAFNS Event Highlight

2026 Food Classification Research Roundtable: Processing, Formulation and Nutrition

March 11-12, 2026

This event will provide attendees with an updated view of the scientific landscape related to food processing, formulation and the intersection with nutrition. To support broad engagement, remote attendance options are available.

GLP-1 Medications

The Science of Safety: Adverse Effects of GLP-1 Receptor Agonists as Glucose-Lowering and Obesity Medications

Journal of Clinical Investigation, 2026

GLP-1 receptor agonist (GLP-1RA) medications have transformed the treatment of type 2 diabetes (T2D) and obesity, with robust evidence for cardiovascular and renal benefits. Nevertheless, GLP-1RA therapy is associated with a pattern of adverse events affecting their safety and tolerability. Here, we delineate mechanisms potentially leading to adverse responses to GLP-1RAs, describe the impact of side effects on treatment persistence, discuss potential mitigation strategies, and identify areas requiring further studies.

IAFNS Event Highlight

Gut Feeling: Toward Development of an AI Tool for Precision Dietary Carbohydrate Recommendations

March 19, 2026

This webinar will provide evidence for individual response to carbohydrates and describe the effort to develop an AI tool for more precise prediction of this response.

Nutrition 2026

NUTRITION 2026

Abstracts due March 9, 2026

Showcase your work at ASN NUTRITION 2026.

IAFNS Research -- Gut Health

Associations Between Live Dietary Microbe Intakes and Cardiometabolic Health in Korean Adults

Journal of Nutrition, 2026

Supported by IAFNS Nutrition for Gut Health Committee

The consumption of live microbes, beyond probiotics, is associated with health benefits. This study aimed to quantify live microbe intake in 2016-2020 Korea National Health and Nutrition Examination Survey (KNHANES) and to investigate the associations between live microbe intake and cardiometabolic health outcomes.

Should I Recommend Foods with Unsaturated Fats?

Part 1: The Scientific Basis for Eating Foods Rich in Unsaturated Fats

April 1, 2026

In the United States, attention and confusion about the role of unsaturated fat-containing foods in the diet is being fueled by debate among some prominent health decision-makers, along with a proliferation of misinformation from media influencers, particularly about polyunsaturated fats. This webinar aimed at practitioners will explore the issues underlying these conversations.

Dietary Patterns

Healthy Dietary Patterns, Longevity Genes, and Life Expectancy: A Prospective Cohort Study

Science Advances, 2026

Associations between healthy dietary patterns and life expectancy remain unclear. Here, we reported the prospective associations of five dietary patterns with mortality and life expectancy in 103,649 UK Biobank participants.

Should I Recommend Foods with Unsaturated Fats?

Part 2: Practical Application of Unsaturated Fats in Health-Promoting Dietary Patterns

April 2, 2026

There is an abundance of conflicting messages about the health impact of unsaturated fats and which foods to eat as well as limit. This webinar series is targeted to health professionals addressing patient and client questions.

Dietary Patterns

Chemical Strategies for Mineral Bioavailability

Nature Food, 2026

Screening a chemical library resulted in the identification of compounds that reduced cereal grain phytic acid content, enhancing mineral bioavailability.

Carbohydrates

Effect of Low-Carbohydrate and Low-Fat Diets on Metabolomic Indices and Coronary Heart Disease in U.S. Individuals

Journal of the American College of Cardiology, 2026

Screening a chemical library resulted in the identification of compounds that reduced cereal grain phytic acid content, enhancing mineral bioavailability.

Protein

Current Progress in Protein Requirement Changes and Associated Factors in the Aging Population

Sci Open, 2026

This review provides a comprehensive analysis of the importance of protein intake among older adults. With the global aging trend accelerating, adequate protein consumption is increasingly recognized as crucial for addressing the decline in muscle mass and function associated with aging.

Low- and No-Calorie Sweeteners

Effects of Non-Nutritive Sweeteners on Weight Loss and Maintenance, Metabolic Improvement, and Appetite Regulation in Weight Management Programs: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Nutrition Reviews, 2026

Achieving and maintaining weight loss remains a clinical challenge, prompting interest in the potential role of non-nutritive sweeteners (NNSs) in weight management. We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) to assess the effects of NNSs on weight loss, weight maintenance, metabolic outcomes, and appetite regulation within weight-management programs.

Cognitive Health

The Association Between Gut Microbiota and Cognitive Decline: A Systematic Review of the Literature

Nutrition Research, 2026

The gut–brain axis has emerged as a key pathway in the pathogenesis of neurodegenerative disorders, with age-related shifts in gut microbiota potentially contributing to cognitive decline and dementia progression. This systematic review evaluated the effects of microbiota-targeted interventions on cognitive outcomes in adults aged >45 years with cognitive impairment or at risk of dementia.

Lipids

Foods Fortified with Soybean or Palm Oil Show No Effect on Inflammation or Oxidized Low-Density Lipoprotein in Adults with Overweight or Obesity: a Secondary Analysis of a Randomized Placebo-Controlled Crossover Trial

Current Developments in Nutrition, 2026

Popular and social media outlets have recent posts claiming that vegetable and seed oils high in linoleic acid (LA) cause inflammation and oxidative stress. However, substantial evidence in the scientific literature shows LA biomarkers are associated with lower risks for type 2 diabetes, cardiovascular disease, and systemic inflammation.

Sodium

Dietary Sodium Reduction and Blood Pressure: A Dose–Response Meta-Analysis in Hypertensive and Chronic Kidney Disease Patients

Clinical Kidney Journal, 2026

Hypertension (HTN) is a leading risk factor for cardiovascular disease, and dietary sodium reduction is a cornerstone strategy for blood pressure (BP) control, particularly in vulnerable populations such as individuals with chronic kidney disease (CKD), who often present with HTN. This study aims to quantify the dose–response relationship between changes in sodium intake and changes in BP.

Emerging Science -- Consumer Apps on Additives

Food Additive Lens: An On-Device AI Application for Real-Time Science-Based Consumer Education on Food Additives using Retrieval-Augmented Generation

Digital Discovery, 2026

This research was supported by IAFNS Assembly on Scientific Integrity

Consumer concerns about food additives have intensified amid widespread misinformation despite authoritative safety data existing in FDA and USDA databases. This paper presents Food Additive Lens (FAL), an iOS application that bridges the gap between scientific knowledge and consumer understanding through on-device artificial intelligence.

Emerging Science -- Improve Consumer Diet Quality

Experimental Evidence from the USA Shows that Recurring Unconditional Cash Transfers Improve the Diets of Low-Income Individuals

Nature Food, 2026

Whether recurring unconditional cash transfers are effective at improving diets in high-income country settings has remained uncertain given competing demands of cash-constrained individuals. Evidence from Massachusetts, USA, demonstrates that recurring unconditional cash transfers reduced caloric deficits and improved consumption of nutritious foods.