Projects Funded by IAFNS

The Institute for the Advancement of Food and Nutrition Sciences catalyzes food safety and nutritional science for the benefit of public health. View projects* funded by IAFNS below.

Application of Acceptable Daily Intake Values in Nutrition Research Studies that Consider the Safety of Low-Calorie Sweeteners

Several recent publications on the intake of low-calorie sweeteners (LCSs) have compared intake data to the corresponding Acceptable Daily Intake (ADI) values. This indicates a use of ADI that may not be appropriate, since ADI is not meant to be […]

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Nutrient Adequacy and Diet Quality in a Randomized Controlled Trial with Normal and Higher Protein Intake

Foods that are high in protein are often rich in other nutrients that are unique to specific categories of foods (e.g., iron in red meat, vitamin E in nuts). When individuals select a protein-containing food on a calorie-controlled diet, it […]

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Impact of New Labeling for Daily Values on Total Nutrient Intakes from Foods and Beverages

Changes to the Nutrition Facts Panel are underway following recently issued regulations by the FDA to correspond with current Institute of Medicine (IOM) Dietary Reference Intakes. However, the expected impact of this new labeling of Daily Values (DVs) on nutrient […]

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Opportunities for Improvement in Nutrition-Related Research: Implications of Overall Quality and Risk of Bias Domain Ratings

Nutrition research informs consumer eating habits, public policy, healthcare practice decisions and research agenda development. Yet, virtually every individual scientific study has limitations in design and methodology. The purpose of this study is to examine these limitations and identify ways […]

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Key Findings and Implications of a Recent Systematic Review of the Potential Adverse Effects of Caffeine Consumption in Healthy Adults, Pregnant Women, Adolescents, and Children

Scientific findings lose their value if they cannot be easily translated for comprehension by diverse audiences. The Institute of Medicine (IOM) also recognizes this fact, and their guidance related to systematic reviews suggests that plain language summaries can improve the […]

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Investigating the Potential Risk of Untargeted Iron Supplementation Among Cambodian Women

There is a lack of evidence on the safety of untargeted daily iron supplementation in women, especially in countries such as Cambodia, where both anemia and genetic hemoglobinopathies are common. Our aim is to assess biomarkers of potential adverse outcomes […]

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Blood Fatty Acid Fingerprint to Predict Risk for Total Mortality

Circulating levels of blood fatty acids are being used to stratify patients into risk categories with regard to the development of chronic disease and death. The fatty acids most clearly associated with reduced risk for cardiovascular disease (CDV) and for […]

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Simulating Large-Number Bulk-Product Sampling to Improve Food Safety Sampling Plans

Drawing an accurate conclusion about whether a food ingredient or product is safe based on the result of a test is important to the evaluation and management of food safety risk. It is critical that sampling plans maximize the probability […]

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Nutritional and Probiotic Development for the Pre-Term Gut Microbiome

The human intestine is home to dense and diverse communities of microorganisms, referred to as the gut microbiota. Ushered by the revolution in “omics,” the microbiota is implicated in numerous health and disease states. Despite the growing recognition of the […]

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Assessing Human Health Impacts of Global Adoption of Codex Deoxynivalenol (DON) Guidelines

Due to climate change, there has been an increase in occurrence of mycotoxins in food and food ingredients. Multiple strategies have been developed to reduce mycotoxin risks before harvest (in the field), after harvest (in storage, transportation, or processing), and […]

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Evaluation of the Dose-Response for Peanut Allergen

Due to the potentially severe nature of the response and absence of approved treatments, allergic individuals have been advised to avoid the food of concern, and food allergens must be included in the ingredients lists of packaged food. However, with […]

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Precision Nutrition: How Combinatory Patterns of SNPs and Nutrition Interact with Mechanistic Elements of Lipid Metabolism

Genetic differences have been shown to explain why blood LDL-cholesterol increases in many people fed dairy fat, but in others this results in a neutral or decreased response LDL response. Likewise, specific genetic modifiers have been shown to predict why […]

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*Projects from 2013 and later are included in this repository. To view projects supported by IAFNS prior to 2013, please visit our Peer-Reviewed Publications page.