Funded Projects

Projects Funded by IAFNS

The Institute for the Advancement of Food and Nutrition Sciences catalyzes food safety and nutritional science for the benefit of public health. View projects* funded by IAFNS below.

Assessing the Relationship between Low-Calorie Sweetener Use and Quality of Life Measures in Adults with Type 1 Diabetes

Low- and No- calorie sweeteners (LNCSs) have been acknowledged as a tool for reducing the intake of total carbohydrates and particularly added sugars in the nutritional management of diabetes. LNCSs may also help to improve Quality of Life (QoL). QoL […]

Broader Dietary Value of Food Category Contributors to Sodium Intake

As noted in the 2020 Dietary Guidelines Advisory Committee report, there is significant overlap between food categories that contribute to sodium intake and to vegetable intake. To ensure appropriate and effective messaging, dietary guidance, and food development or modification, it […]

Impact of Ingested Live Microbes on Health: An evidence Map

Human gut microbiome research has linked imbalances in the gut microbiota with several suboptimal health conditions. Consequently, the application of dietary interventions including foods (i.e., fermented foods [FFs]) and food supplements (i.e., probiotics) that contain live microorganisms to positively […]

Specific Essential Amino Acid Intakes and Health Benefits Among Older Adults

Protein and specific amino acid intakes are among the lifestyle factors that can mitigate muscle loss among older adults. Lean mass is associated with metabolic and functional health in older age. Clear linkages between specific amino acids and health outcomes […]

The Identification of Microbially-Derived Metabolites as Biomarkers: What Changes of Which Metabolites Matter for Health?

Identifying microbially‐derived metabolites that may serve as biomarkers for health, or metabotyping, is a necessary step to understanding the role of the microbiome in human health. Ultimately, knowing what metabolites (including presence and quantity) matter for health can inform development […]

Development of a Research Framework for Evidence-Based Assessment of Potential Carcinogens in Human Diets

Risk assessment of chemicals that are potentially carcinogenic in humans often relies on extrapolation from carcinogenicity bioassays. There is a growing belief in the scientific community that evidence-based risk assessment can replace historical, over-protective guidance-based approaches. However, there is no […]

Impact of Dietary Sweetness Exposure on Future Dietary Intake: Reanalysis of Existing Intervention Trial Data

Several global health authorities recommend avoidance of sweetness in the diet from both sugar and low-calorie or non-nutritive sweeteners, due to concerns that intake of sweet taste drives a preference for more sweetness, with ultimate negative consequences for energy intake […]

Effect of Low-Calorie Sweetener Intake on Glycemic Response

Globally, dietary guidance recommends reducing added and total sugars in the diet to reduce caloric intake and chronic disease. Low-calorie sweeteners (LCS) present an option for reducing calories while providing sweetness in the diet, but questions remain regarding the effects […]

Standardizing Method and Development of Normal Values to Measure Human Small Intestinal and Colonic Permeability

Maintaining-or restoring to normal-gut barrier function is not currently recognized as a physiologic benefit of fiber consumption, in part due to lack of agreement by experts in the field on how to define and measure normal gut barrier function in […]

Metabolic and Physiological Properties of Rare Sugars Review Paper

Rare sugars are monosaccharides or disaccharides that exist in small quantities in nature and have unique metabolic and physiological properties that help distinguish them from more commonly consumed sugars like fructose and glucose. Due to their unique properties, rare sugars […]

Global Comparison of How Short-Term Blood Glucose Response to Food is Measured and Translated

The wide range of methods used to describe the impact of food on short-term glycemic response makes it challenging to apply research results broadly, including but not limited to its use on food labels. The choice of approach should be […]

Updating the Metal Dietary Exposure Screening Tool

The IAFNS Food and Chemical Safety Committee invests in the training and education of future scientists and leaders in the fields of food and chemical safety and food toxicology by supporting a Summer Fellowship Program for doctoral students. This project […]

*Projects from 2013 and later are included in this repository. To view projects supported by IAFNS prior to 2013, please visit our Peer-Reviewed Publications page.