Funded Projects

Projects Funded by IAFNS

The Institute for the Advancement of Food and Nutrition Sciences catalyzes food safety and nutritional science for the benefit of public health. View projects* funded by IAFNS below.

Bacteriophage Engineering for Rapid Pathogen Detection

The development of pragmatic rapid detection methods benefit the food manufacturer, retailer and consumer. It has been estimated that cost of foodborne illness from sickness, hospitalizations and deaths reaches $152 billion annually in the United States. Although the United States […]

Systematic Review of the Health Effects Associated with Consumption of Caffeine in Humans

To date, one of the most heavily cited assessments of caffeine safety in the peer-reviewed literature is that issued by Health Canada (Nawrot et al., 2003). Since then, >10,000 papers have been published related to caffeine. An update to this […]

Perinatal Choline Status and Cognitive Function

Perinatal nutrition plays a critical role in neurodevelopmental patterns, and specific periods of sensitivity have been identified during which deficiency of even a single nutrient can negatively impact long-term cognitive and behavioral measures. Recent human and rodent studies suggest provision […]

Evaluation of Arsenic-Induced Intracytoplasmic Inclusions

Intracytoplasmic inclusions have been observed in various cell types in individuals exposed to high levels of inorganic arsenic in the drinking water or diet and have been classified as micronuclei. However, in our laboratory, we have observed identical types of […]

Evidence Mapping of Low-Calorie Sweeteners and Health Outcomes

As concerns regarding the link between added sugars and obesity risk rise, there is increasing interest in low-calorie sweeteners (LCSs) as a common replacement of added sugars to help reduce total energy intake and reduce excess body weight. In 2012, […]

Development of a Fortification Database

The aim of this project is to develop a database of enriched, fortified, and intrinsic nutrient levels for all foods reported consumed in the 2007-2008, 2009-2010 WWEIA, NHANES, and also the2011-2012 WWEIA, NHANES, which provides the most recent nationally representative […]

Evaluating the Association between Dietary Exposure to Inorganic Arsenic on Health Outcomes for the US Population

Chronic adverse health effects have been observed with exposure to high levels of inorganic arsenic. The health effects related to lower levels inorganic arsenic exposure have not been established. The aim of this study is to evaluate longitudinal cohort studies […]

Partially Hydrogenated Oils: Dose Response Evaluation

There is evidence of a significant dose-dependent linear relationship between industrial trans fatty acids (iTFA) intake from partially hydrogenated oils and low-density lipoprotein cholesterol (LDL-C), a validated surrogate marker of coronary heart disease risk. The aim of this study is to […]

An Approach to Standardize the Concepts of Low Dose and Nonmonotonic Dose Response in Toxicological Research and Regulatory Science

The IAFNS Food and Chemical Safety Committee invests in the training and education of future scientists and leaders in the fields of food and chemical safety and food toxicology by supporting a Summer Fellowship Program for doctoral students. This project […]

Quantitative Modeling for Biomarker Assessment of Carbohydrate Metabolism

It is now appreciated that the many pathways leading to oncogenesis result in changes in cellular metabolism and the ability of the tumors environmental nutritional state to directly couple to its capacity for growth. One of the first molecularly defined […]

Identifying Genomic and Microbiome Influence on Response to Dietary Interventions for Improved Lipid Parameters

Metabolic syndrome, whose clinical manifestations include central obesity, hypertension, dyslipidemia, and elevated glucose levels, results in greatly increased risk of developing cardiovascular disease and diabetes. Changes in diet and physical activity can prevent and even reverse manifestations of metabolic syndrome, […]

Trans Fatty Acids and Cholesterol Levels: An Evidence Map of the Available Science

The aim of this project is to characterize the existing literature regarding intervention trials on industrial trans fatty acid intake as a substitute for cis-monounsaturated fatty acids or saturated fatty acids and resulting changes in LDL- or HDL-cholesterol. Institution: Biofortis […]

*Projects from 2013 and later are included in this repository. To view projects supported by IAFNS prior to 2013, please visit our Peer-Reviewed Publications page.