Lutein/Zeaxanthin and Eye Health Visual Function Evidence Map and Systematic Review

Lutein/zeaxanthin, found in egg yolks and a variety of fruits and vegetables, is associated with healthy ocular tissue, but an amount recommended per day has not been established. The goal of this study is to determine the strength of evidence linking a specific quantity of lutein/zeaxanthin with normal healthy eye structure (including macular pigment density) and visual function among populations relevant to general population in North America. In Phase I, an evidence map will be developed to summarize the extent and distribution of evidence to provide investigators with information about the type and amount of research available, the characteristics of that research, and the topics where a sufficient amount of evidence has accumulated for synthesis. In Phase II, specific defined outcome(s) from the evidence map will be selected for systematic evidence review.

Institution: Jean Mayer USDA HNRCA at Tufts University
Principal Investigator: Elizabeth Johnson, PhD
Year Awarded: 2015

Read more: Lutein/Zeaxanthin Intake and Visual Outcomes in Adults with Healthy Eyes: Qualitative Gap Analysis

Read more: The Association Between Macular Pigment Optical Density and Visual Function Outcomes: A Systematic Review and Meta-Analysis

Read more: The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis


Learn more about the IAFNS Bioactives Committee.