Food Chemical Safety Science at IAFNS

The IAFNS Food Chemical Safety Committee mobilizes members from government, industry and academia to drive, fund and lead actionable science in support of public health.

Improving Food Safety

Through its tripartite model—bringing together scientists from governmentacademia, and industry—the Food Chemical Safety Committee funds external researchers and convenes experts to enhance the safety of our global food supply.

Focus Areas include:

  • Heavy Metals and Toxic Elements
  • Nanoplastics and Microplastics
  • Food Allergens
  • Evidence-Based Risk Assessment
  • New Approach Methods (NAMs)

Chemicals and Food Safety

The Food Chemical Safety Committee promotes a science-based assessment of the safety of foods and food ingredients to support public health.

For example, our work advances strategies for mitigating the presence of heavy metals in food and agricultural soils.

We fund and promote novel, exposure-focused risk assessment methods that leverage validated new approaches and scientific paradigms.

Lab Assistant with Foodstuffs
Advancing Exposure Assessment for Food Contaminants Through Implementation of Probabilistic Modeling
Principles for Food Classification Focused on Processing and Formulation

Explore recent publications and events from the Food Chemical Safety Committee.

Join Us >

Committee Members

FOCUS AREAS

Heavy Metals

Soil Factors Driving Uptake of Toxic Elements by Rice and Leafy Greens

Both rice and leafy greens are healthy, widely consumed, and used in a variety of food products, but are susceptible to contamination by toxic elements, sometimes referred to as heavy metals. Rice is a uniquely grown crop, typically grown under flooded conditions for most of its lifecycle, which increases availability of arsenic. Leafy greens, including the widely consumed lettuce and spinach, can be contaminated by toxic elements including cadmium and lead. Spinach is particularly efficient at accumulating cadmium in its leaves. This work examines the soil factors that drive uptake of arsenic and cadmium in rice and cadmium and lead in leafy greens to highlight how soil factors, by very different mechanisms, are important in driving this uptake in diverse food products. This information informs mitigation solutions.

A Framework for Heavy Metal Exposure Reduction in Human Diets

Heavy metals (also referred to as toxic elements) such as lead, cadmium, mercury and arsenic are widely present in the environment due to natural occurrence (e.g., in agricultural soils) and anthropomorphic activities. Heavy metals can sometimes unavoidably enter the food supply from various routes such as soil, water and air, as well as agricultural practices. Aligned with FDA’s ‘Closer to Zero’ initiative for reducing toxic elements in foods for babies and infants, the committee has launched two complementary research projects that aim to develop a framework for reducing exposure to heavy metals in foods. Framework elements will include metal/commodity prioritization, concentration ranges, exposure assessments, agricultural practices, and current and future mitigation options along the production and supply chains.

Review of Regulatory Reference Values and Background Levels for Heavy Metals in the Human Diet

The U.S. Food and Drug Administration has identified dietary exposure to heavy metals as a public health concern, focusing particularly on arsenic, cadmium, lead and mercury. One way to assess exposure risk is to compare established safe exposure limits (reference values) with current population-based dietary background levels. In this IAFNS paper, information on reference values and dietary background exposure was quickly evaluated and updated. These regulatory and consumption levels inform a novel, interactive, web-based tool that can be used for screening-level assessments of potential risks of heavy metals in foods and ingredients.

Heavy Metals and Age Groups

Heavy metals such as arsenic (As), cadmium (Cd), lead (Pb), and mercury (Hg) have the potential to cause neurocognitive impairment to infants and young children who are exposed to them in their diets. To help address these risks it is important to identify which foods contain the highest levels of these metals; and based on US consumption of these foods by age group, which food-metal combinations cause the greatest potential exposure via diets. This research examined which foods contain the highest levels of heavy metals; and based on US consumption of these foods by different age groups, which food-metal dyads cause the greatest human exposures.

Microplastics
Risk Assessment
NAMs
Food Allergens

Projects Supported by the Committee

Evidence-Based Risk Assessment of Ingredients and Additives

Ingredient & Additive Risk Assessment Evidence-Based Risk Assessment of Ingredients and Additives This project focuses on the development of a framework to facilitate the risk […]

Soil Factors Driving Uptake of Toxic Elements by Rice and Leafy Greens

Investigating Soil Characteristics Soil Factors Driving Uptake of Toxic Elements by Rice & Leafy Greens Investigating how soil characteristics influence arsenic, cadmium, and lead levels […]

Exposure Characterization of Micro- and Nanoplastics in Foods

FCS and Packaging Committee Project: Exposure Characterization of Micro- and Nanoplastics in Foods The volume of plastics produced globally every year has steadily increased over […]

Review of EU Novel Food Submissions and US GRAS Petitions to Identify Opportunities for NAMS

Opportunities for NAMS in Food Safety Reviews Review of EU Novel Food Submissions and US GRAS Petitions to Identify Opportunities for NAMS The risk assessment […]

Heavy Metals in US Foods: Exposure Assessment by Age Group and Mitigation Strategies

Heavy Metal Exposure in US Foods by Age Group Heavy Metals in US Foods: Exposure Assessment by Age Group and Mitigation Strategies Heavy metals such […]

A Framework for Heavy Metal Prioritization and Mitigation for Reducing Metal Intake: Rice and Spinach Case Studies

Heavy Metal Risk and Mitigation in Rice and Spinach A Framework for Heavy Metal Prioritization and Mitigation for Reducing Metal Intake: Rice and Spinach Case […]

Sharing Our Science

Committee Publications

Concentrations of Cadmium and Arsenic Species in Rice from Production-Scale Fields in Arkansas under Variable Water Management

Rice accumulates arsenic when grown under flooded conditions; therefore, alternative water management strategies have shown promise in decreasing grain arsenic. This paper analyzes polished white rice grain from 103 field-years of production for arsenic and cadmium.

Read more about Concentrations of Cadmium and Arsenic Species in Rice from Production-Scale Fields in Arkansas under Variable Water Management

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Committee Events

IAFNS at IAFP 2023

Toronto, Canada

Each year, the International Association for Food Protection hosts an Annual Meeting, providing attendees with information on current and emerging food safety issues.

Read more about IAFNS at IAFP 2023

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Join IAFNS at the IAFP 2023 Annual Meeting July 16-19, 2023 in Toronto, Ontario, Canada: https://www.foodprotection.org/annualmeeting/

Genomics in Food Safety- How to Use the Tools to Prevent Outbreaks Expand

Convenor: Heather Carleton, CDC

Speakers:

  • Martin Wiedmann, Cornell University
  • Yan Luo, FDA
  • Jessie Heidenreich, Hilmar Cheese Company

Date and Time: Monday, July 17, 2023 from 10:45AM-12:15PM

Event Link: https://iafp.confex.com/iafp/2023/onlineprogram.cgi/Session/8847

Data Sharing in the Digital Age of Food Safety Expand

Convenor: Kathy Glass, University of Wisconsin

Panelist:

  • De Ann Davis, Western Growers Association
  • Angie Siemens, Cargill
  • Sophia Santillana-Farakos, FDA
  • James Doyle, Crème Global
  • Marie Breton, Health Canada

Date and Time: Monday, July, 17, 2023 from 3:45 to 5:15 PM

Event Link: https://iafp.confex.com/iafp/2023/onlineprogram.cgi/Session/8849

Investigating Ambiguous Outbreaks and Adverse Events Expand

Convenor: Laurie Post (Deibel Labs) and Kelly Dawson (Conagra Brands)

Speakers:

  • Craig Hedberg, University of Minnesota
  • Tim Jackson, FDA
  • Michael Vasser, CDC
  • Mitzi Baum, STOP Foodborne Illness

Date and Time: Wednesday, July 19, 2023 from 1:30-3:30 PM

Event Link: https://iafp.confex.com/iafp/2023/onlineprogram.cgi/Session/8835

From Farm to Food: A New Perspective on Heavy Metals in Human Diets Expand Convenor: Paul Hanlon, Abbott Nutrition Speakers:
  • Benjamin Runkle, University of Arkansas
  • Felicia Wu, Michigan State University
  • Kevin Boyd, The Hershey Company
Date and Time: Tuesday, July 18, 2023, from 4:45 PM - 5:15 PM Event Link: https://iafp.confex.com/iafp/2023/onlineprogram.cgi/Session/8577 [post_title] => IAFNS at IAFP 2023 [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => iafns-at-iafp-2023 [to_ping] => [pinged] => [post_modified] => 2025-07-17 10:31:32 [post_modified_gmt] => 2025-07-17 14:31:32 [post_content_filtered] => [post_parent] => 0 [guid] => https://iafns.org/?post_type=event&p=31927 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 29610 [post_author] => 343 [post_date] => 2022-09-30 19:21:50 [post_date_gmt] => 2022-09-30 19:21:50 [post_content] => [post_title] => Federal and State Efforts to Restrict PFAS: Impact on Food Companies [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => pfas-impact-on-food-companies [to_ping] => [pinged] => [post_modified] => 2022-11-17 03:46:06 [post_modified_gmt] => 2022-11-17 03:46:06 [post_content_filtered] => [post_parent] => 0 [guid] => https://iafns.org/?post_type=event&p=29610 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 2 [current_post] => -1 [before_loop] => [in_the_loop] => [post] => WP_Post Object ( [ID] => 31927 [post_author] => 2 [post_date] => 2023-06-26 10:05:39 [post_date_gmt] => 2023-06-26 14:05:39 [post_content] =>

Join IAFNS at the IAFP 2023 Annual Meeting July 16-19, 2023 in Toronto, Ontario, Canada: https://www.foodprotection.org/annualmeeting/

Genomics in Food Safety- How to Use the Tools to Prevent Outbreaks Expand

Convenor: Heather Carleton, CDC

Speakers:

  • Martin Wiedmann, Cornell University
  • Yan Luo, FDA
  • Jessie Heidenreich, Hilmar Cheese Company

Date and Time: Monday, July 17, 2023 from 10:45AM-12:15PM

Event Link: https://iafp.confex.com/iafp/2023/onlineprogram.cgi/Session/8847

Data Sharing in the Digital Age of Food Safety Expand

Convenor: Kathy Glass, University of Wisconsin

Panelist:

  • De Ann Davis, Western Growers Association
  • Angie Siemens, Cargill
  • Sophia Santillana-Farakos, FDA
  • James Doyle, Crème Global
  • Marie Breton, Health Canada

Date and Time: Monday, July, 17, 2023 from 3:45 to 5:15 PM

Event Link: https://iafp.confex.com/iafp/2023/onlineprogram.cgi/Session/8849

Investigating Ambiguous Outbreaks and Adverse Events Expand

Convenor: Laurie Post (Deibel Labs) and Kelly Dawson (Conagra Brands)

Speakers:

  • Craig Hedberg, University of Minnesota
  • Tim Jackson, FDA
  • Michael Vasser, CDC
  • Mitzi Baum, STOP Foodborne Illness

Date and Time: Wednesday, July 19, 2023 from 1:30-3:30 PM

Event Link: https://iafp.confex.com/iafp/2023/onlineprogram.cgi/Session/8835

From Farm to Food: A New Perspective on Heavy Metals in Human Diets Expand Convenor: Paul Hanlon, Abbott Nutrition Speakers:
  • Benjamin Runkle, University of Arkansas
  • Felicia Wu, Michigan State University
  • Kevin Boyd, The Hershey Company
Date and Time: Tuesday, July 18, 2023, from 4:45 PM - 5:15 PM Event Link: https://iafp.confex.com/iafp/2023/onlineprogram.cgi/Session/8577 [post_title] => IAFNS at IAFP 2023 [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => iafns-at-iafp-2023 [to_ping] => [pinged] => [post_modified] => 2025-07-17 10:31:32 [post_modified_gmt] => 2025-07-17 14:31:32 [post_content_filtered] => [post_parent] => 0 [guid] => https://iafns.org/?post_type=event&p=31927 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) [comment_count] => 0 [current_comment] => -1 [found_posts] => 8 [max_num_pages] => 4 [max_num_comment_pages] => 0 [is_single] => [is_preview] => [is_page] => [is_archive] => 1 [is_date] => [is_year] => [is_month] => [is_day] => [is_time] => [is_author] => [is_category] => [is_tag] => 1 [is_tax] => [is_search] => [is_feed] => [is_comment_feed] => [is_trackback] => [is_home] => [is_privacy_policy] => [is_404] => [is_embed] => [is_paged] => 1 [is_admin] => [is_attachment] => [is_singular] => [is_robots] => [is_favicon] => [is_posts_page] => [is_post_type_archive] => [query_vars_hash:WP_Query:private] => 1a11c4c857723c0a9388ef0e0c2d873f [query_vars_changed:WP_Query:private] => [thumbnails_cached] => [allow_query_attachment_by_filename:protected] => [stopwords:WP_Query:private] => [compat_fields:WP_Query:private] => Array ( [0] => query_vars_hash [1] => query_vars_changed ) [compat_methods:WP_Query:private] => Array ( [0] => init_query_flags [1] => parse_tax_query ) [query_cache_key:WP_Query:private] => wp_query:338edb4622e428af969fce4199d35e0d )