At the Institute for the Advancement of Food and Nutrition Sciences research serves as the foundation for our actions. See our current grant opportunities below.

Current Opportunities:

Assessing the Relationship between Low-Calorie Sweetener (LCS) Use and Quality of Life Measures in Individuals with Diabetes

Please indicate your preliminary interest in applying for funding under this RFP by writing to Marie Latulippe at no later than January 9, 2021.

Using LCSs in place of added sugars allows more room in the healthy eating plan for other sources of carbohydrate, such as whole grains, fruit, and vegetables, while potentially satisfying the desire for sweet taste. LCSs in place of added sugars can also help reduce total carbohydrate intake. In turn, LCSs may be a helpful tool in type 1 or type 2 diabetes to manage post-prandial blood glucose levels. QoL is an important aspect in management of diabetes, as reduced QoL can negatively affect diabetes-related outcomes. Effective blood glucose control is also associated with better QoL in children with diabetes, suggesting that decreased QoL may negatively impact successful diabetes management. This knowledge may also be useful to clinicians who field questions about the general utility of LCSs, particularly when there has been increasing public misunderstanding of both their safety and efficacy for various intended outcomes.

Links between one’s eating plan and QoL have been studied previously, but links between use of LCSs within eating plans and QoL have not been studied. A recent systematic review sponsored by the World Health Organization that was designed to investigate the effects of LCS use for people with diabetes included health-related QoL as an outcome measure. However, authors did not identify any data in the peer-reviewed literature that met the inclusion-exclusion criteria specified. Authors concluded that data on this “patient-important outcome” were “scarce or lacking.

For the study under this Request for Proposals, IAFNS is seeking input from applicants on appropriate survey selection as well as design and incorporation of questions about use of LCSs. The objective is to assess the relationship between use of LCSs and health-related Quality of Life (QoL) measures in adults or families with children residing in North America that were diagnosed with diabetes (types 1 or 2) not less than 1 year ago.

Please submit proposals by 11:59 p.m. ET on January 30, 2021 to Marie Latulippe (

Scientific integrity is a core value of IAFNS. Learn how we embed scientific integrity into every step of our research process.

Projects Funded by IAFNS:

IAFNS's mission is to advance food safety and nutrition science for the benefit of public health. View projects funded by IAFNS below, and learn how we embed scientific integrity into every step of our research process.

Sampling of Post-Hurricane Florence Floodwater for Human Foodborne Pathogens

Heavy rainfall and flooding following a hurricane can massively impact water quality, especially via runoff from agricultural and industrial operations. The IAFNS Food Microbiology Committee is supporting researchers at North Carolina State University to examine the emergence, potential routes of contamination and proliferation, as well as virulence and susceptibility of three major foodborne pathogens in […]

Application of Acceptable Daily Intake Values in Nutrition Research Studies that Consider the Safety of Low-Calorie Sweeteners

Several recent publications on the intake of low-calorie sweeteners (LCSs) have compared intake data to the corresponding Acceptable Daily Intake (ADI) values. This indicates a use of ADI that may not be appropriate, since ADI is not meant to be considered a threshold for a safety concern at one moment in time. This may lead […]

Nutrient Adequacy and Diet Quality in a Randomized Controlled Trial with Normal and Higher Protein Intake

Foods that are high in protein are often rich in other nutrients that are unique to specific categories of foods (e.g., iron in red meat, vitamin E in nuts). When individuals select a protein-containing food on a calorie-controlled diet, it is at the expense of other foods in the diet. It is unclear what foods […]

Impact of New Labeling for Daily Values on Total Nutrient Intakes from Foods and Beverages

Changes to the Nutrition Facts Panel are underway following recently issued regulations by the FDA to correspond with current Institute of Medicine (IOM) Dietary Reference Intakes. However, the expected impact of this new labeling of Daily Values (DVs) on nutrient values is unknown. The objective of this project is to use the 2009-2010 and 2011-2012 […]

Opportunities for Improvement in Nutrition-Related Research: Implications of Overall Quality and Risk of Bias Domain Ratings

Nutrition research informs consumer eating habits, public policy, healthcare practice decisions and research agenda development. Yet, virtually every individual scientific study has limitations in design and methodology. The purpose of this study is to examine these limitations and identify ways to improve scientific methods and in turn, research quality, in the future. Institution: EF Myers […]

Key Findings and Implications of a Recent Systematic Review of the Potential Adverse Effects of Caffeine Consumption in Healthy Adults, Pregnant Women, Adolescents, and Children

Scientific findings lose their value if they cannot be easily translated for comprehension by diverse audiences. The Institute of Medicine (IOM) also recognizes this fact, and their guidance related to systematic reviews suggests that plain language summaries can improve the work’s usability for general audiences (IOM, 2009). Thus, the aim of this paper is to […]

Investigating the Potential Risk of Untargeted Iron Supplementation Among Cambodian Women

There is a lack of evidence on the safety of untargeted daily iron supplementation in women, especially in countries such as Cambodia, where both anemia and genetic hemoglobinopathies are common. Our aim is to assess biomarkers of potential adverse outcomes in Cambodian women who received daily oral iron supplements in accordance with the recent 2016 […]

Blood Fatty Acid Fingerprint to Predict Risk for Total Mortality

Circulating levels of blood fatty acids are being used to stratify patients into risk categories with regard to the development of chronic disease and death. The fatty acids most clearly associated with reduced risk for cardiovascular disease (CDV) and for death from any cause are the marine omega-3 fatty acids, EPA and DHA. However, these […]

Simulating Large-Number Bulk-Product Sampling to Improve Food Safety Sampling Plans

Drawing an accurate conclusion about whether a food ingredient or product is safe based on the result of a test is important to the evaluation and management of food safety risk. It is critical that sampling plans maximize the probability of finding a target hazard in an ingredient or a finished product, particularly with non-uniform […]

Nutritional and Probiotic Development for the Pre-Term Gut Microbiome

The human intestine is home to dense and diverse communities of microorganisms, referred to as the gut microbiota. Ushered by the revolution in “omics,” the microbiota is implicated in numerous health and disease states. Despite the growing recognition of the significance of the microbiota, there are fundamental aspects of the microbiota that are largely unexplored […]

Assessing Human Health Impacts of Global Adoption of Codex Deoxynivalenol (DON) Guidelines

Due to climate change, there has been an increase in occurrence of mycotoxins in food and food ingredients. Multiple strategies have been developed to reduce mycotoxin risks before harvest (in the field), after harvest (in storage, transportation, or processing), and in diets. Developed nations have stricter limits for mycotoxins as compared to developing nations. Strict […]

Evaluation of the Dose-Response for Peanut Allergen

Due to the potentially severe nature of the response and absence of approved treatments, allergic individuals have been advised to avoid the food of concern, and food allergens must be included in the ingredients lists of packaged food. However, with statements such as “may contain allergen X” or “also packaged in a facility that contains […]