At the Institute for the Advancement of Food and Nutrition Sciences research serves as the foundation for our actions. See our current grant opportunities below.

Current Opportunities:

Assessing the Relationship between Low-Calorie Sweetener (LCS) Use and Quality of Life Measures in Individuals with Diabetes

Please indicate your preliminary interest in applying for funding under this RFP by writing to Marie Latulippe at mlatulippe@iafnsconnect.wpengine.com no later than January 9, 2021.

Using LCSs in place of added sugars allows more room in the healthy eating plan for other sources of carbohydrate, such as whole grains, fruit, and vegetables, while potentially satisfying the desire for sweet taste. LCSs in place of added sugars can also help reduce total carbohydrate intake. In turn, LCSs may be a helpful tool in type 1 or type 2 diabetes to manage post-prandial blood glucose levels. QoL is an important aspect in management of diabetes, as reduced QoL can negatively affect diabetes-related outcomes. Effective blood glucose control is also associated with better QoL in children with diabetes, suggesting that decreased QoL may negatively impact successful diabetes management. This knowledge may also be useful to clinicians who field questions about the general utility of LCSs, particularly when there has been increasing public misunderstanding of both their safety and efficacy for various intended outcomes.

Links between one’s eating plan and QoL have been studied previously, but links between use of LCSs within eating plans and QoL have not been studied. A recent systematic review sponsored by the World Health Organization that was designed to investigate the effects of LCS use for people with diabetes included health-related QoL as an outcome measure. However, authors did not identify any data in the peer-reviewed literature that met the inclusion-exclusion criteria specified. Authors concluded that data on this “patient-important outcome” were “scarce or lacking.

For the study under this Request for Proposals, IAFNS is seeking input from applicants on appropriate survey selection as well as design and incorporation of questions about use of LCSs. The objective is to assess the relationship between use of LCSs and health-related Quality of Life (QoL) measures in adults or families with children residing in North America that were diagnosed with diabetes (types 1 or 2) not less than 1 year ago.

Please submit proposals by 11:59 p.m. ET on January 30, 2021 to Marie Latulippe (mlatulippe@iafnsconnect.wpengine.com).

Scientific integrity is a core value of IAFNS. Learn how we embed scientific integrity into every step of our research process.

Projects Funded by IAFNS:

IAFNS's mission is to advance food safety and nutrition science for the benefit of public health. View projects funded by IAFNS below, and learn how we embed scientific integrity into every step of our research process.

Precision Nutrition: How Combinatory Patterns of SNPs and Nutrition Interact with Mechanistic Elements of Lipid Metabolism

Genetic differences have been shown to explain why blood LDL-cholesterol increases in many people fed dairy fat, but in others this results in a neutral or decreased response LDL response. Likewise, specific genetic modifiers have been shown to predict why cholesterol-lowering plant sterols are highly effective in many people, but not in others. Customizing dietary […]

Best Practices for the Design, Laboratory Analysis, and Reporting of Trials Involving Fatty Acids

Differences in how samples are collected, analyzed, and reported hamper research reproducibility and translation into dietary guidance. The goal of this project is to develop best practices for measuring and reporting circulating fatty acids in blood. The resulting best practices are intended to improve reproducibility in studies in which blood fatty acids are reported, by […]

Evaluating the Applicability of Read-Across Tools and High-Throughput Screening Data for Food Relevant Chemicals

The IAFNS Food and Chemical Safety Committee invests in the training and education of future scientists and leaders in the fields of food and chemical safety and food toxicology by supporting a Summer Fellowship Program for doctoral students. This project focused on Evaluating the Applicability of Read-Across Tools and High-Throughput Screening Data for Food Relevant […]

Camp DASH Ancillary Studies

The Camp DASH study trial will compare the effect of two dietary patterns and two levels of sodium intake on blood pressure and blood lipids in adolescents in the upper third of distribution for blood pressure. The two dietary patterns are based on the Dietary Approaches to Stop Hypertension (DASH) trial in adults. Purdue University […]

Vitamin B12 and Perinatal Health: Elucidating Mechanisms and Biomarkers for Prevention of Birth Defects

Neural tube defects (NTDs) are one of the most common and severe birth defects in the United States and globally. Vitamin B12 deficiency and perturbations in one-carbon metabolism have been linked to common adverse pregnancy outcomes, including neural tube closure defects. Recent evidence from population studies have identified vitamin B12 deficiency as the leading nutritional […]

Impact of Fortification/Enrichment on Total Nutrient Intakes from Foods within Specific Groups by Socioeconomic Status

As part of its review every five years, the Dietary Guidelines Advisory Committee (DGAC) estimates the nutrient intake of the American population and identifies those nutrients of national concern. The Scientific Report of the 2015 DGAC identified “shortfall nutrients” and “overconsumed nutrients” and assessed which of those nutrients posed “substantial” public health concern. The aims […]

Novel Estimation of Energy Balance through the Calibration of Consumer Devices in Free-Living, Rural US Children

Children in rural areas are disproportionately affected by pediatric obesity. The American Heart Association has listed delivery of obesity treatment to rural families using mobile health (mHealth) as a major research priority. Improving the estimation of energy intake and balance is a priority for developing successful mHealth obesity treatment programs. The aims of this project […]

Dietary Patterns Associated with Cognition During Aging

In 2011, 15% of Canadians 65 and older were living with Alzheimer’s disease (AD), the most common form of dementia. Despite the fact that the cause of AD is not known, age and the presence of the epsilon 4 allele of apolipoprotein E (APOE4) are the most important risk factors.  Diet is central to health […]

Survival and Inactivation of Bacterial and Viral Pathogens in Model Low-Moisture Foods

Low-moisture food (LMF) products are often ingredients (e.g. nuts, dried fruits, cereal products, and chocolate) used in the manufacture of many food products. Because of this, they carry significant potential for the amplification of outbreaks and recalls over a wide variety of products. There has been worldwide recognition of the need to more seriously manage […]

Comparison and Analysis of Toxcast Data with In Vivo Data for Food-Relevant Compounds Using The Risk21 Approach

The IAFNS Food and Chemical Safety Committee invests in the training and education of future scientists and leaders in the fields of food and chemical safety and food toxicology by supporting a Summer Fellowship Program for doctoral students. This project focused on Comparison and Analysis of Toxcast Data with In Vivo Data for Food-Relevant Compounds […]

Demonstrating the Causal Beneficial Role of Microbes in Diet-Microbe-Host Interactions in Metabolic Disease

Over the past decade there has been an exponentially growing number of reports that describe changes in the microbial populations in response to dietary intervention. These changes in the microbiota are then associated with health outcomes with limited understanding of what changes in the microbial population really mean. Very few reports have demonstrated the specific […]

Listeria monocytogenes Thermal Resistance in Low-Moisture Foods: Role of Water Activity or Food Matrix

Low moisture foods (e.g., cocoa powder, dried milk powder, flour) have been increasingly involved in foodborne outbreaks. Foodborne pathogens such as Listeria monocytogenes can survive in low moisture foods and dry food processing environments for months, and even for years. However, there is a general lack of knowledge related to the behavior of L. monocytogenes […]