Journal of Nutrition. 2009;139:1269S-1270S
Abstract: This article highlights the discussion of the issues that had been raised during the International Life Sciences Institute North America- and USDA Agricultural Research Service-sponsored workshop surrounding the consumption of fructose. One conclusion of the discussion was that the metabolic effects of high-fructose corn syrup (HFCS) and sucrose appear to be similar in humans. However, there have been few studies directly comparing the effects of fructose to other caloric sweeteners, such as glucose, HFCS, and sucrose. Differential effects may include those related to insulin sensitivity, triglyceride and lipoprotein levels, and glycated protein levels. Further exploration of the differences between nutritive sweeteners should be the basis of a research agenda. Studies should also further investigate factors that might affect the results, such as the amount and form of the sweetener consumed, the macronutrient composition of the basal diet, the length of the study, and the characteristics of the subjects. Meanwhile, health professionals could help consumers by providing simple messages, such as the importance of consuming lower levels of energy, including those from all caloric sweeteners.
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Supplement Contents
- Jones JM. Dietary Sweeteners Containing Fructose: Overview of a Workshop on the State of the Science. Journal of Nutrition. 2009;139(6):1210S-1213S.
- Borra ST, Bouchoux A. Effects of Science and the Media on Consumer Perceptions About Dietary Sugars. Journal of Nutrition. 2009;139(6):1214S-1218S.
- White JS. Misconceptions About High-Fructose Corn Syrup: Is It Uniquely Responsible for Obesity, Reactive Dicarbonyl Compounds, and Advanced Glycation Endproducts?. Journal of Nutrition. 2009;139(6):1219S-1227S.
- Marriott BP, Cole N, Lee E. National Estimates of Dietary Fructose Intake Increased from 1977 to 2004 in the United States. Journal of Nutrition. 2009;139(6):1228S-1235S.
- Stanhope KL, Havel PJ. Fructose Consumption: Considerations For Future Research on Its Effects on Adipose Distribution, Lipid Metabolism, and Insulin Sensitivity in Humans. Journal of Nutrition. 2009;139(6):1236S-1241S.
- Angelopoulos TJ, Lowndes J, Zukley L, et al.. The Effect of High-Fructose Corn Syrup Consumption on Triglycerides and Uric Acid. Journal of Nutrition. 2009;139(6):1242S-1245S.
- Livesey G. Fructose ingestion: Dose-Dependent Responses in Health Research. Journal of Nutrition. 2009;139(6):1246S-1252S.
- Moran TH. Fructose and Satiety. Journal of Nutrition. 2009;139(6):1253S-1256S.
- Schaefer EJ, Gleason JA, Dansinger ML. Dietary Fructose and Glucose Differentially Affect Lipid and Glucose Homeostasis. Journal of Nutrition. 2009;139(6):1257S-1262S.
- Bantle JP. Dietary Fructose and Metabolic Syndrome and Diabetes. Journal of Nutrition. 2009;139(6):1263S-1268S.
- Murphy SP. The State of the Science on Dietary Sweeteners Containing Fructose: Summary and Issues to Be Resolved. Journal of Nutrition. 2009;139:1269S–1270S.
This work was supported by the IAFNS Committee on Carbohydrates.