Quantitative Microbiome Profiling and Identification of a Cross-Disease Enterotype Linked to Depression and Wellbeing

IAFNS Gut Microbiome Webinar Series
Virtual, Webinar
March 3, 2021
10:30 am – 11:30 am

Alterations in the gut microbiota have been linked to various pathologies, ranging from inflammatory bowel disease and diabetes to cancer. Although large numbers of clinical studies aiming at microbiome-based disease markers are currently being performed, our basic knowledge about the normal variability of the human intestinal microbiota and its determining factors remains limited. Here, Dr. Raes will discuss his findings studying a large-scale study (Flemish Gut Flora Project; n=3400) of the gut microbiome variation in a geographically confined region (Flanders, Belgium), in which analysis of microbiome variability in health identified the primary parameters associated to microbiome composition. In this presentation, Dr. Raes will discuss his laboratory’s experiences in large-scale microbiome monitoring, how the development of dedicated computational approaches can assist in microbiome analysis and interpretation, and which confounders are essential for inclusion in microbiome disease research. The presentation will address how Quantitative Microbiome Profiling is profoundly changing our view on gut microbiota variation and has allowed the identification of an inflammation-associated, cross-disease enterotype.

Speaker:
Jeroen Raes, PhD, KU Leuven

This webinar can be watched here.

Learn more about the IAFNS Gut Microbiome Committee.