Conducting a Systematic Review for a Global Audience: Challenges in Merging Nutrition and Toxicological Evidence for a Safety Assessment of Caffeine
April 22, 2017
Chicago, Illinois, USA
Experimental Biology 2017
April 21, 2017 – April 25, 2017
Chicago, Illinois, USA
IAFNS supported various sessions at the 2017 Experimental Biology Conference.
Society of Toxicology Annual Meeting 2017 & Expo
March 12, 2017 – March 16, 2017
Baltimore, MD, USA
The Food and Chemical Safety Committee will be sponsoring multiple projects being presented at the SOT Annual Meeting.
Read more about Society of Toxicology Annual Meeting 2017 & Expo
Workshop: State of the Science on Alternatives to Animal Testing and Integration of Testing Strategies for Food Safety Assessments
February 28, 2017
College Park, MD, USA
- Harris Lieberman, US Army - Behavior - Video
- Charles O'Brien, University of Pennsylvania - Behavior - Video (See Lieberman for pdf)
- Jennifer Peck, PhD University of Oklahoma - Reproductive & Developmental Toxicity - Video
- Daniele Wikoff on behalf of Jeffrey Goldberger, University of Miami, Miller School of Medicine- Cardiovascular - Video
- Connie Weaver, PhD, Purdue University - Bone & Calcium - Video
- Milton Tenenbein, MD, University of Manitoba - Acute & Pharmacokinetics - Video
Moderated by Dennis Keefe, PhD
Panel includes: 6 of the 7 Scientific Advisory Board members, Daniele Wikoff of ToxStrategies (Scientific Review Team), Alison Kretser of IAFNS (Oversight Committee) Overall Conclusions - presented by Daniele Wikoff
Full session playlist
See IAFNS's other sessions at Experimental Biology 2017:
Full Schedule Learn more [post_title] => Conducting a Systematic Review for a Global Audience: Challenges in Merging Nutrition and Toxicological Evidence for a Safety Assessment of Caffeine [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => experimental-biology-2017-2 [to_ping] => [pinged] => [post_modified] => 2021-02-09 16:44:05 [post_modified_gmt] => 2021-02-09 16:44:05 [post_content_filtered] => [post_parent] => 0 [guid] => https://iafnsconnect.wpengine.com/?post_type=event&p=2388 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 2386 [post_author] => 343 [post_date] => 2017-03-24 17:02:46 [post_date_gmt] => 2017-03-24 17:02:46 [post_content] => Conducting a Systematic Review for a Global Audience: Challenges in Merging Nutrition and Toxicological Evidence for a Safety Assessment of CaffeineSaturday, 22 April 2017
8:30AM - 12:30PM
Ballroom S100BC
Speakers: Dennis Keefe, FDA; Harris Lieberman, USARIEM; Esther Myers, EF Myers Consulting; Charles O'Brien, University of Pennsylvania; Jennifer Peck, University of Oklahoma; Milton Tenenbein, University of Manitoba; Connie Weaver, Purdue University; Daniele Wikoff, ToxStrategies
Supported by the Caffeine Working Group
Session Info & Videos The Changing Brain: How Brain Plasticity, Exercise and Nutrition Affect Function and Cognition
Saturday, 22 April 2017
3:00PM - 5:00PM,
Ballroom S100BC
- Neurogensis and brain plasticity in the adult brain - Henriette van Praag, National Institute on Aging;
- The Relation of Exercise, fitness, & Adiposity to Cognitive and Brain Health - Charles Hillman, University of Illinois - Video
- Neuroinflammatory Processes in Cognitive Disorders - Sophie Laye, Universite Bordeaux - Video
- Exercise, Nutrition and Brain Funciton: What are the steps toward dietary and physical activity Recommendations? - Mary Ann Johnson, University of Georgia - Video
- Panel Discussion - Video
Sunday, 23 April 2017
8:30AM- 10:30AM
S105BCD
Speakers:
- Intro to Predictive Modeling: From Linear Regression Models to Mechanistic Mathematical Modeling - David Allison, University of Alabama at Birmingham - Video;
- Use of Predictive Modeling in the Design of Clinical Studies Kevin Hall, NIDDK - Video;
- Application of Predictive Modeling in Weight Loss Counseling - Corby Martin, Pennington Biomedical Research Center - Video;
- Application of Predictive Modeling in Personalized Nutrition - Ben van Ommen, TNO - Video;
- Utility of PRedictive Modeling for Public Health Obesity Policies - Emily Dhurandhar, Texas Tech University - Video;
- Summary and Wrap-Up - Diana Thomas, West Point - Video
Supported by the Protein Committee - Full session playlist
Tuesday, 25 April 2017
11:00AM - 12:30PM
S105AB
Speakers: Kara Livingston, Tufts University; Caleigh Sawicki, Tufts University
Supported by the Carbohydrate Committee Posters
Sources of dietary folate/folic acid in women of different races in the United States between 2009 and 2012: What is the role of fortified and enriched products?
Abstract Number: 6707
Poster Board Number C88
Presenter: Ray DeVirgiliis, George Washington University
Monday, 24 April
1:45PM-2:45PM [post_title] => Experimental Biology 2017 [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => experimental-biology-2017 [to_ping] => [pinged] => [post_modified] => 2023-01-23 04:48:49 [post_modified_gmt] => 2023-01-23 04:48:49 [post_content_filtered] => [post_parent] => 0 [guid] => https://iafnsconnect.wpengine.com/?post_type=event&p=2386 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 2203 [post_author] => 343 [post_date] => 2017-01-11 23:16:59 [post_date_gmt] => 2017-01-11 23:16:59 [post_content] => [post_title] => Society of Toxicology Annual Meeting 2017 & Expo [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => society-of-toxicology-annual-meeting-2017-expo [to_ping] => [pinged] => [post_modified] => 2017-06-23 13:26:01 [post_modified_gmt] => 2017-06-23 13:26:01 [post_content_filtered] => [post_parent] => 0 [guid] => https://iafnsconnect.wpengine.com/?post_type=event&p=2203 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 2252 [post_author] => 343 [post_date] => 2017-02-01 18:46:35 [post_date_gmt] => 2017-02-01 18:46:35 [post_content] =>
Co-hosted by U.S. Food and Drug Administration, Center for Food Safety & Applied Nutrition (CFSAN) and the IAFNS Technical Committee on Food & Chemical Safety
This workshop will bring together scientists from government, academia and industry to discuss the advances in testing strategies to reduce animal testing and the need for the development of a standardized approach for use of these alternative methodologies in food safety assessment.
Workshop Proceedings:
State of the Science on Alternatives to Animal Testing and Integration of Testing Strategies for Food Safety Assessments
Read the Proceedings Registration ExpandThere is no fee to attend the workshop but, registration is required by Tuesday, February 21. Please register for the workshop using this link: Workshop Registration
Webcast RegistrationRegister for webcast here: webcast registration
Webcast participants can submit questions online during the event. These will be answered as time allows. Agenda Expand
8:30-8:40 am: Welcome Suzanne Fitzpatrick, FDA Mansi Krishan, IAFNS
8:40-8:55amIntroductory Remarks
Dennis Keefe, FDA
Heidi Bialk, IAFNS Member Scientist 8:55-9:35am
Integrated Testing Strategies in Food Safety
Alan Boobis, Imperial College London [30 mins + 10 mins Q & A] 9:35-10:15am
State of the Science on High Through-Put Screening (HTS): Food Safety Perspective
Nadine Bewry, FDA 10:30-11:10am
Case Studies to Describe the Limitations of Using HTS data in Food Safety Assessment
Rebecca Clewell, ScitoVation 11:10 -11:50am
Identify and Translate Learnings from On-Going Assay Validation Efforts into Standard HTS Testing Practices
Richard Judson, EPA 12:50- 1:30pm
Read Across Approaches: Chemical Structure and Bioactivity Profiling Applicable to Food Safety
Grace Patlewicz, EPA 1:30-2:10pm
FDA Perspective on Read Across Approaches
Tim Adams, FDA 2:10-2:50 pm
Organ on a Chip Technology
Daniel Levner, Emulate 3:05- 4:30pm
Panel Discussion Moderator: Suzanne Fitzpatrick, FDA Panelists:
All speakers, Thomas Hartung, Johns Hopkins University and Katya Tsaioun, Johns Hopkins University 4:30-4:40pm
Concluding Remarks
Suzanne Fitzpatrick
FDA Mansi Krishan, IAFNS Videos Expand
A video of the workshop can be found on the FDA YouTube channel
[post_title] => Workshop: State of the Science on Alternatives to Animal Testing and Integration of Testing Strategies for Food Safety Assessments [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => animaltestingworkshop [to_ping] => [pinged] => [post_modified] => 2019-11-20 19:06:18 [post_modified_gmt] => 2019-11-20 19:06:18 [post_content_filtered] => [post_parent] => 0 [guid] => https://iafnsconnect.wpengine.com/?post_type=event&p=2252 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 4 [current_post] => -1 [before_loop] => [in_the_loop] => [post] => WP_Post Object ( [ID] => 2388 [post_author] => 343 [post_date] => 2017-03-24 19:37:55 [post_date_gmt] => 2017-03-24 19:37:55 [post_content] => Official Program About this session ExpandWhile the role of systematic reviews becomes more fully appreciated, the quality of systematic reviews is inconsistent. As the field of systematic reviews evolves, there are an increasing number of frameworks and approaches that can be used to conduct such comprehensive research. When conducting systematic reviews there are questions about how to: develop a protocol and PICO (Population, Intervention, Comparator, Outcome) questions, execute a search strategy, manage data, grade the literature, evaluate and manage biases, and ensure transparency of the process. This session will address these components by using a large multi-endpoint systematic review of caffeine which followed the framework of the IOM Report "Finding What Works in Health Care: Standards for Systematic Reviews", as a case study.
There continues to be interest within the scientific community in what is a safe level of caffeine intake and if certain populations should have modified recommendations. Since the 2003 release of the highly cited and valued review by Nawrot et al., "Effects of caffeine on human health", there have been more than 5,000 articles on the effects of caffeine in humans published, highlighting the need for an update to this body of work.
The Systematic Review of the effects of caffeine on human health took into account the challenges of including nutrition and toxicological evidence. The health endpoints reviewed for caffeine are: acute toxicity, behavior, bone and calcium homeostasis, cardiovascular health, developmental and reproductive toxicity, and pharmacokinetics in three healthy populations. The session will present the lessons learned and will emphasize the efforts taken to ensure transparency and rigor that allow for the achievement of a high level of scientific quality. Specific areas of focus will include challenges with identifying and integrating caffeine intakes by level of adversity (e.g., physiological or clinical endpoints), and difficulties in applying standard risk of bias tools across outcomes and endpoints.
Although this session will focus on the Caffeine Systematic Review as a case study, the process, findings, and lessons are relevant to nutrition researchers and professionals who utilize systematic reviews.
Agenda & Videos Expand WelcomeAlison Kretser, MS, RD, IAFNS The Caffeine Landscape - framing the need for the Systematic Review
Dennis Keefe, PhD, FDA
Video Striving for the Gold Standard in the Systematic Review Process
Esther Myers, PhD, RDN, FAND, EF Myers Consulting
Video The Methodology and Challenges of the Caffeine Systematic Review
Daniele Wikoff, PhD, ToxStrategies
Video Q&A
Moderated by Dennis Keefe, PhD
Video
10:10 - 10:25 Break
General Results of the Systematic ReviewDaniele Wikoff, PhD, ToxStrategies
Video
Results of Specific Health Endpoints- Scientific Advisory Board Members
- Harris Lieberman, US Army - Behavior - Video
- Charles O'Brien, University of Pennsylvania - Behavior - Video (See Lieberman for pdf)
- Jennifer Peck, PhD University of Oklahoma - Reproductive & Developmental Toxicity - Video
- Daniele Wikoff on behalf of Jeffrey Goldberger, University of Miami, Miller School of Medicine- Cardiovascular - Video
- Connie Weaver, PhD, Purdue University - Bone & Calcium - Video
- Milton Tenenbein, MD, University of Manitoba - Acute & Pharmacokinetics - Video
Moderated by Dennis Keefe, PhD
Panel includes: 6 of the 7 Scientific Advisory Board members, Daniele Wikoff of ToxStrategies (Scientific Review Team), Alison Kretser of IAFNS (Oversight Committee) Overall Conclusions - presented by Daniele Wikoff
Full session playlist
See IAFNS's other sessions at Experimental Biology 2017:
Full Schedule Learn more [post_title] => Conducting a Systematic Review for a Global Audience: Challenges in Merging Nutrition and Toxicological Evidence for a Safety Assessment of Caffeine [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => experimental-biology-2017-2 [to_ping] => [pinged] => [post_modified] => 2021-02-09 16:44:05 [post_modified_gmt] => 2021-02-09 16:44:05 [post_content_filtered] => [post_parent] => 0 [guid] => https://iafnsconnect.wpengine.com/?post_type=event&p=2388 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) [comment_count] => 0 [current_comment] => -1 [found_posts] => 19 [max_num_pages] => 4 [max_num_comment_pages] => 0 [is_single] => [is_preview] => [is_page] => [is_archive] => [is_date] => [is_year] => [is_month] => [is_day] => [is_time] => [is_author] => [is_category] => [is_tag] => [is_tax] => [is_search] => [is_feed] => [is_comment_feed] => [is_trackback] => [is_home] => 1 [is_privacy_policy] => [is_404] => [is_embed] => [is_paged] => 1 [is_admin] => [is_attachment] => [is_singular] => [is_robots] => [is_favicon] => [is_posts_page] => [is_post_type_archive] => [query_vars_hash:WP_Query:private] => b692340bd2edd989c384be3e1209b726 [query_vars_changed:WP_Query:private] => [thumbnails_cached] => [allow_query_attachment_by_filename:protected] => [stopwords:WP_Query:private] => [compat_fields:WP_Query:private] => Array ( [0] => query_vars_hash [1] => query_vars_changed ) [compat_methods:WP_Query:private] => Array ( [0] => init_query_flags [1] => parse_tax_query ) )2015
EPA Workshop on Advancing Systematic Review for Chemical Advancement
December 16, 2015 – December 17, 2015
Arlington, Virginia, USA
This workshop featured presentations on the ongoing Systematic Review on caffeine being done by IAFNS.
Read more about EPA Workshop on Advancing Systematic Review for Chemical Advancement
Physical Activity and Energy Balance: Public Health Priorities for the Americas
November 9, 2015
Punta Cana, Dominican Republic
IAFNS and ILSI North Andean organized a session on “Physical Activity and Energy Balance: Public Health Priorities for the Americas.”
Read more about Physical Activity and Energy Balance: Public Health Priorities for the Americas
Characterizing Sodium and Potassium Intakes and Their Ratio in the American Diet
October 5, 2015
Nashville, Tennessee, USA
Dr. Reagan Bailey presented on “Characterizing Sodium and Potassium Intakes and Their Ratio in the American Diet” at the FNCE 2015 Poster Session.
Read more about Characterizing Sodium and Potassium Intakes and Their Ratio in the American Diet
Health Risk Assessment of Oral Exposure to Arsenic
September 26, 2015 – September 30, 2015
New Orleans, Louisiana, USA
The IAFNS Food & Chemical Safety Committee sponsored this session at the Environmental Mutagenesis and Genomics Society (EMGS) Annual Meeting.
Read more about Health Risk Assessment of Oral Exposure to Arsenic
The Safety of Sodium Reduction in the Food Supply: A Cross Discipline Balancing Act
September 22, 2015
Washington, DC, USA
This workshop was a collaboration between the IAFNS Technical Committees on Food Microbiology and Sodium.
Read more about The Safety of Sodium Reduction in the Food Supply: A Cross Discipline Balancing Act