Projects Funded by IAFNS

The Institute for the Advancement of Food and Nutrition Sciences catalyzes food safety and nutritional science for the benefit of public health. View projects* funded by IAFNS below.

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Quantitative Modeling for Biomarker Assessment of Carbohydrate Metabolism

It is now appreciated that the many pathways leading to oncogenesis result in changes in cellular metabolism and the ability of the tumors environmental nutritional state to directly couple to its capacity for growth. One of the first molecularly defined […]

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Identifying Genomic and Microbiome Influence on Response to Dietary Interventions for Improved Lipid Parameters

Metabolic syndrome, whose clinical manifestations include central obesity, hypertension, dyslipidemia, and elevated glucose levels, results in greatly increased risk of developing cardiovascular disease and diabetes. Changes in diet and physical activity can prevent and even reverse manifestations of metabolic syndrome, […]

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Trans Fatty Acids and Cholesterol Levels: An Evidence Map of the Available Science

The aim of this project is to characterize the existing literature regarding intervention trials on industrial trans fatty acid intake as a substitute for cis-monounsaturated fatty acids or saturated fatty acids and resulting changes in LDL- or HDL-cholesterol. Institution: Biofortis […]

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Correlation of Surrogate Bacteria and Salmonellae for Validation of Spice/Herb Pathogen Reduction Processes

Spices and herbs are obtained from plants that are grown in open fields and later subjected to a drying process that often involves sun drying in open environments. Therefore, bacterial pathogens are likely to be present in these products. Despite […]

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Development of a Fiber Database and Evidence Map

Thousands of studies have been completed on a wide range of fiber and fiber-rich foods examining a wide range of health outcomes. The aim of this project is to develop a comprehensive database of fibers to enable efficient conduct of […]

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Protocol and Surrogate Validation for the Inactivation of Salmonella on Spices

Worldwide, spices are used to enhance the flavor of foods. In many cultures, spices are considered ready-to-eat and are added to foods after cooking, creating some risk for consumers if the spices have been contaminated with human pathogens. Several outbreaks […]

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Low-Calorie Sweeteners and Body Weight and Composition

Replacement of caloric sweeteners with lower- or no calorie alternatives may facilitate weight loss or weight maintenance by helping to reduce energy intake. However, past research examining the relationship between low-calorie sweeteners (LCSs) and body weight has produced mixed results. […]

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Toxicology and Risk Assessment of Chemical Mixtures

The IAFNS Food and Chemical Safety Committee invests in the training and education of future scientists and leaders in the fields of food and chemical safety and food toxicology by supporting a Summer Fellowship Program for doctoral students. This project […]

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Nutrition-Toxicity Interactions in Daphnia pulex: Developing an Alternative Model Organism for Early Life Exposures

As a well-known eco-toxicological model organism, Daphnia pulex may also offer advantages in human health research for assessing long-term effects of early life exposures to coupled stressors. This study will serve as a proof-of-concept for the use of Daphnia pulex […]

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Future Research Needs Assessment for Fructose/Sugar and Health Outcomes

The aim of this project is to identify research gaps and prioritize research needs related to dietary sugars and potentially related health outcomes. Institution: Tufts University Principal Investigator: Mei Chung, PhD Year Awarded: 2013 Read more: Research needs and prioritizations […]

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Forging an Understanding of the Double-Edged Iron Sword and Immunity

Upon infection, the host and pathogen compete to acquire, utilize and store essential iron. The goal of this project is to understand how iron nutrition contributes to infectious disease pathogenesis and clinical outcomes. This information can be utilized to determine […]

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Evaluation of Food-Relevant Chemicals in ToxCast Phase II

The IAFNS Food and Chemical Safety Committee invests in the training and education of future scientists and leaders in the fields of food and chemical safety and food toxicology by supporting a Summer Fellowship Program for doctoral students. This project […]

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*Projects from 2013 and later are included in this repository. To view projects supported by IAFNS prior to 2013, please visit our Peer-Reviewed Publications page.