The Nutrition for Gut Health Committee advances and communicates the scientific understanding of the impact of diet and dietary constituents on gut and host health.

(This Committee represents the evolution of the Gut Microbiome Committee.)

Strategic Focus Area

  • Advance shared definitions and approaches to measurement of gut health and gut microbiome across stakeholders.
  • Evaluate and advance the evidence for nutrition support of optimal gut and host health.
  • Communicate the evidence that underpins how diets and dietary constituents impact measures of gut health and other systems influenced by gut physiology.
  • Through the Live Dietary Microbes Subcommittee, gather, develop, and drive science- and evidence-based decisions on dietary recommendations for live microbes (learn more here). See news story about the promise of research on dietary microbes for health.

Current Work

This committee has various work underway:

Webinar Series

The Committee has initiated a webinar series to help guide the committee’s research and projects.

Access the Webinar Series

COMMITTEE MEMBERS

Abbott Nutrition
General Mills
Mondelēz International
National Dairy Council

ACADEMIC ADVISORS

Marla Cunningham, MS, ISAPP

Wendy A. Henderson, PhD, CRNP, School of Nursing, University of Pennsylvania

Johanna Lampe, PhD, RD, Fred Hutchinson Cancer Center

Gary D. Wu, MD, Perelman School of Medicine, University of Pennsylvania

GOVERNMENT ADVISORS

Cindy Davis, PhD, USDA, ARS
Lauren VieBrock, PhD, US FDA
William Yan, PhD, Health Canada (Retired)

Join Us!

Projects Supported by the Committee:

Investigation of the Relationship Between Live Dietary Microbe Intake and Health Outcomes, Using the Korean National Health and Nutrition Examination Survey (KNHANES)

Understanding and Advancing Best Practices for Human Nutrition & Gut Microbiome Research

Sample Collection, Preservation, and Data Analysis in Gut Microbiome Research: Current Methods and Potential Impact on Results

Development of a Human Whole-Stool Reference Material – NIST Collaboration

Impact of Ingested Live Microbes on Health: An evidence Map

The Identification of Microbially-Derived Metabolites as Biomarkers: What Changes of Which Metabolites Matter for Health?

Publications

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Oldest to Newest

Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions

The Journal of Nutrition, 2019

IAFNS previously took on the task of defining a “healthy gut microbiome,” and the outcome of this effort was published by Backhed et al. in 2012. Since that time, the body of work on gut microbiome has grown exponentially. In 2018, >40 invited academic, government, and industry experts gathered to evaluate progress toward this definition and explore the question: Can a Healthy Gut Microbiome be Defined Through Quantifiable Characteristics?

Read more about Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions

Workshop Report: Toward the Development of a Human Whole Stool Reference Material for Metabolomic and Metagenomic Gut Microbiome Measurements

Metabolomics, 2020

This report represents the consensus opinions of workshop participants on developing general criteria for metabolite selection and a preliminary list of proposed metabolites. The paper describes some of the strengths and limitations of this initiative given the current state of gut microbiome research.

Read more about Workshop Report: Toward the Development of a Human Whole Stool Reference Material for Metabolomic and Metagenomic Gut Microbiome Measurements

Diet-Related and Gut-Derived Metabolites and Health Outcomes: A Scoping Review.

Metabolites, 2022

A scoping review to map evidence about the health impact of gut microbiota-derived metabolites is now available. The researchers found a need to conduct more prospective studies, including clinical trials. Researchers identified metabolites and conditions for which systematic reviews are warranted to characterize the direction and magnitude of metabolite-disease associations.

Read more about Diet-Related and Gut-Derived Metabolites and Health Outcomes: A Scoping Review.

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                            [key] => _ilsi_date
                            [compare] => =
                            [compare_key] => =
                            [alias] => wp_postmeta
                            [cast] => CHAR
                        )

                    [mt1] => Array
                        (
                            [key] => _ilsi_date
                            [value] => 2019-05-20
                            [compare] => >=
                            [type] => DATE
                            [compare_key] => =
                            [alias] => mt1
                            [cast] => DATE
                        )

                    [mt2] => Array
                        (
                            [key] => _ilsi_date
                            [value] => Array
                                (
                                    [0] => 2025-01-01
                                    [1] => 2025-12-31
                                )

                            [compare] => BETWEEN
                            [compare_key] => =
                            [alias] => mt2
                            [cast] => CHAR
                        )

                )

            [has_or_relation:protected] => 
        )

    [date_query] => 
    [request] => 
					SELECT SQL_CALC_FOUND_ROWS  wp_posts.ID
					FROM wp_posts  LEFT JOIN wp_term_relationships ON (wp_posts.ID = wp_term_relationships.object_id) INNER JOIN wp_postmeta ON ( wp_posts.ID = wp_postmeta.post_id )  INNER JOIN wp_postmeta AS mt1 ON ( wp_posts.ID = mt1.post_id )  INNER JOIN wp_postmeta AS mt2 ON ( wp_posts.ID = mt2.post_id )
					WHERE 1=1  AND ( 
  wp_term_relationships.term_taxonomy_id IN (440)
) AND ( 
  wp_postmeta.meta_key = '_ilsi_date' 
  AND 
  ( 
    ( mt1.meta_key = '_ilsi_date' AND CAST(mt1.meta_value AS DATE) >= '2019-05-20' ) 
    AND 
    ( mt2.meta_key = '_ilsi_date' AND mt2.meta_value BETWEEN '2025-01-01' AND '2025-12-31' )
  )
) AND ((wp_posts.post_type = 'event' AND (wp_posts.post_status = 'publish' OR wp_posts.post_status = 'acf-disabled')))
					GROUP BY wp_posts.ID
					ORDER BY wp_postmeta.meta_value ASC
					LIMIT 0, 5
				
    [posts] => Array
        (
        )

    [post_count] => 0
    [current_post] => -1
    [before_loop] => 
    [in_the_loop] => 
    [comment_count] => 0
    [current_comment] => -1
    [found_posts] => 0
    [max_num_pages] => 0
    [max_num_comment_pages] => 0
    [is_single] => 
    [is_preview] => 
    [is_page] => 
    [is_archive] => 1
    [is_date] => 
    [is_year] => 
    [is_month] => 
    [is_day] => 
    [is_time] => 
    [is_author] => 
    [is_category] => 
    [is_tag] => 1
    [is_tax] => 
    [is_search] => 
    [is_feed] => 
    [is_comment_feed] => 
    [is_trackback] => 
    [is_home] => 
    [is_privacy_policy] => 
    [is_404] => 
    [is_embed] => 
    [is_paged] => 
    [is_admin] => 
    [is_attachment] => 
    [is_singular] => 
    [is_robots] => 
    [is_favicon] => 
    [is_posts_page] => 
    [is_post_type_archive] => 
    [query_vars_hash:WP_Query:private] => 62682b0e2c930fe83a6f6d4b8bb9d845
    [query_vars_changed:WP_Query:private] => 
    [thumbnails_cached] => 
    [allow_query_attachment_by_filename:protected] => 
    [stopwords:WP_Query:private] => 
    [compat_fields:WP_Query:private] => Array
        (
            [0] => query_vars_hash
            [1] => query_vars_changed
        )

    [compat_methods:WP_Query:private] => Array
        (
            [0] => init_query_flags
            [1] => parse_tax_query
        )

)