The Nutrition for Gut Health Committee advances and communicates the scientific understanding of the impact of diet and dietary constituents on gut and host health.

(This Committee represents the evolution of the Gut Microbiome Committee.)

Strategic Focus Area

  • Advance shared definitions and approaches to measurement of gut health and gut microbiome across stakeholders.
  • Evaluate and advance the evidence for nutrition support of optimal gut and host health.
  • Communicate the evidence that underpins how diets and dietary constituents impact measures of gut health and other systems influenced by gut physiology.
  • Through the Live Dietary Microbes Subcommittee, gather, develop, and drive science- and evidence-based decisions on dietary recommendations for live microbes (learn more here). See news story about the promise of research on dietary microbes for health.

Read an Op-Ed 'Showcasing the Benefits of Fermented Foods,' in Food Ingredients. Pages 48-49.

Current Work

This committee has various work underway:

Webinar Series

The Committee has initiated a webinar series to help guide the committee’s research and projects.

COMMITTEE MEMBERS

Abbott Nutrition
General Mills
Kraft Heinz
Mondelēz International
National Dairy Council

ACADEMIC ADVISORS

Marla Cunningham, MS, ISAPP

Wendy A. Henderson, PhD, CRNP, School of Nursing, University of Pennsylvania

Johanna Lampe, PhD, RD, Fred Hutchinson Cancer Center

Gary D. Wu, MD, Perelman School of Medicine, University of Pennsylvania

GOVERNMENT ADVISORS

Cindy Davis, PhD, USDA, ARS

Publications

Best Practices and Considerations for Conducting Research on Diet-Gut Microbiome Interactions and their Impact on Health in Adult Populations: An Umbrella Review

Finding causal links between diet-gut microbiome interactions and health is complicated by variability in research methods and reporting. 

Read more about Best Practices and Considerations for Conducting Research on Diet-Gut Microbiome Interactions and their Impact on Health in Adult Populations: An Umbrella Review

Methods in Nutrition & Gut Microbiome Research: An American Society for Nutrition Satellite Session

The microbial cells in the human gut form an ecosystem that regulates and maintains human health. IAFNS has joined the American Society for Nutrition in an effort to harmonize approaches to studying the gut microbiome to better explore these connections. The scientific session summarized how improving the accuracy, precision and comparability of microbiome research will build understanding of the associations between the microbiome, health and disease prevention.

Read more about Methods in Nutrition & Gut Microbiome Research: An American Society for Nutrition Satellite Session

Mapping the Available Evidence on the Impact of Ingested Live Microbes on Health: A Scoping Review Protocol

Some researchers think that the regular consumption of safe, live microbes confers health-promoting attributes, including the prevention of disease. To address this hypothesis, we propose a scoping review to assess the large amount of scientific literature that is now available on this topic.

Read more about Mapping the Available Evidence on the Impact of Ingested Live Microbes on Health: A Scoping Review Protocol

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Events

The Role of the Gut Structure and Function in Health and Disease: The Celiac Disease Paradigm

Virtual, Event

The intestine is a critical site for interaction between the host and the external environment. Its complex structure plays key roles in selective absorption of nutrients or other dietary or environmental components, with implications for local and systemic effects which will be explored in this webinar.

Read more about The Role of the Gut Structure and Function in Health and Disease: The Celiac Disease Paradigm

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                    [post_title] => Everyone Wants It, But What Is It? Understanding How ‘Gut Health’ is Defined and Implications for Nutrition Professionals
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                    [post_content] => 

	

IAFNS is presenting at the American Society for Nutrition Annual Meeting - NUTRITION 2025 - and will showcase new work on funded projects.

Session Topic for NUTRITION 2025:

What is 'Gut Health'? From Research Concepts to Implementation. Expand

"Gut health" has become a part of the common lexicon to describe health in a broader sense. In marketing campaigns, gut health is often a catchall phrase that can mean any number of health-promoting outcomes. While gut health lacks a clear definition, the term is increasingly used in human and veterinary medicine, but there are unanswered questions: Is gut health different from digestive health or GI health? What is the overall importance of gut health for individuals who do not have bowel disease?  How should gut health be measured? For the latter, a variety of criteria have been proposed, but not yet agreed-upon. In this session, work by experts will be presented to shed light on what constitutes a healthy gut and how that is measured, with implications for scientific, industrial, and regulatory communities. Presented in collaboration with the International Scientific Association for Probiotics and Prebiotics (ISAPP).

Speakers:

Moderator Opening: Conceptualization of Gut Health: Historical Context and Current Thinking - A Physician's Perspective

Gary Wu, MD, University of Pennsylvania

Current Science of Nutrition and Gut Health
Maria Marco, PhD, University of California, Davis Measuring Gut Health - From Research to Practice
Cara Frankenfeld, PhD, Epidstrategies LLC

Panel will include time for Q&A

Associations Between Live Dietary Microbe Intakes and Health Outcomes, Analyses of the KHANES 2016-2020 Data Expand Abstract Submission ID: 2036119
Abstract Title:  Presenting Author: Yue Zhan
Poster Session: Nutritional Microbiology/Microbiome/Microbiome Nutrition (Poster Session)
Poster Session Date: 
6/1/2025

Abstract

Objectives: The consumption of live microbes, beyond probiotics, is associated with health benefits.1,2 This study aimed to quantify live microbe intake in 2016-2020 South Korean National Health and Nutrition Examination Survey (KNHANES), and to investigate the associations between live microbe intake and health outcomes.

Methods: We developed a KNHANES live microbe classification system based on the Sanders system3 and divided KNHANES food codes that overlapped with NHANES into four categories: no live microbe or low (<104 CFU/g), medium (104-107 CFU/g), and high (>107 CFU/g) levels. Microbe data on various types of kimchi were obtained from World Kimchi Institute and data on other non-overlapping food codes were determined based on literature and authoritative reviews. We performed descriptive analyses on live microbe intakes among adults aged 19 y and older. We then conducted survey-weighted adjusted regression analyses to evaluate the relationship between live microbe intake and cardiometabolic health outcomes, controlling for age, sex, body mass index, household income, physical activity level, current smoking status, and alcohol intake.

Results: The mean daily intake of medium live microbe foods was 179.48 g in the South Korean population, while high live microbe foods averaged 122.49 g. Kimchi contributed a significant portion, with a mean intake of 102.44 g. An additional 100-g intake of medium or high live microbe-containing foods was associated with a lower C-reactive protein (coefficient: -0.006; 95% CI: -0.01, -0.002 mg/dL) and a lower weight (coefficient: 0.06; 95% CI: 0.041, 0.038 kg). The associations were significantly different among age groups. We did not find statistically significant associations between live microbe intake and other health outcomes.

Conclusions: This study provides new data on dietary intakes of live microbes and their potential health benefits in a nationally representative data set of South Korean adults.

Funding source: Institute for the Advancement of Food and Nutrition Sciences.

 

For more information on the NUTRITION 2025 conference, click here.

For more information on the presentation, email: science@iafns.org

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