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							Official Program
					
			About this session
							Expand
		

While the role of systematic reviews becomes more fully appreciated, the quality of systematic reviews is inconsistent. As the field of systematic reviews evolves, there are an increasing number of frameworks and approaches that can be used to conduct such comprehensive research.  When conducting systematic reviews there are questions about how to: develop a protocol and PICO (Population, Intervention, Comparator, Outcome) questions, execute a search strategy, manage data, grade the literature, evaluate and manage biases, and ensure transparency of the process. This session will address these components by using a large multi-endpoint systematic review of caffeine which followed the framework of the IOM Report "Finding What Works in Health Care: Standards for Systematic Reviews", as a case study.

There continues to be interest within the scientific community in what is a safe level of caffeine intake and if certain populations should have modified recommendations.  Since the 2003 release of the highly cited and valued review by Nawrot et al., "Effects of caffeine on human health", there have been more than 5,000 articles on the effects of caffeine in humans published, highlighting the need for an update to this body of work.

The Systematic Review of the effects of caffeine on human health took into account the challenges of including nutrition and toxicological evidence. The health endpoints reviewed for caffeine are: acute toxicity, behavior, bone and calcium homeostasis, cardiovascular health, developmental and reproductive toxicity, and pharmacokinetics in three healthy populations.  The session will present the lessons learned and will emphasize the efforts taken to ensure transparency and rigor that allow for the achievement of a high level of scientific quality.  Specific areas of focus will include challenges with identifying and integrating caffeine intakes by level of adversity (e.g., physiological or clinical endpoints), and difficulties in applying standard risk of bias tools across outcomes and endpoints.

Although this session will focus on the Caffeine Systematic Review as a case study, the process, findings, and lessons are relevant to nutrition researchers and professionals who utilize systematic reviews.

Agenda & Videos Expand Welcome
Alison Kretser, MS, RD, IAFNS The Caffeine Landscape - framing the need for the Systematic Review 
Dennis Keefe, PhD, FDA
Video Striving for the Gold Standard in the Systematic Review Process
Esther Myers, PhD, RDN, FAND, EF Myers Consulting
Video The Methodology and Challenges of the Caffeine Systematic Review
Daniele Wikoff, PhD, ToxStrategies
Video Q&A
Moderated by Dennis Keefe, PhD
Video

10:10 - 10:25 Break

General Results of the Systematic Review
Daniele Wikoff, PhD, ToxStrategies
Video

Results of Specific Health Endpoints- Scientific Advisory Board Members

  • Harris Lieberman, US Army - Behavior - Video 
  • Charles O'Brien, University of Pennsylvania - Behavior - Video (See Lieberman for pdf)
  • Jennifer Peck, PhD University of Oklahoma - Reproductive & Developmental Toxicity - Video 
  • Daniele Wikoff on behalf of Jeffrey Goldberger, University of Miami, Miller School of Medicine- Cardiovascular - Video 
  • Connie Weaver, PhD, Purdue University - Bone & Calcium - Video 
  • Milton Tenenbein, MD, University of Manitoba - Acute & Pharmacokinetics - Video 
Panel Discussion with the Caffeine Systematic Review Project Team Members Video
Moderated by Dennis Keefe, PhD
Panel includes: 6 of the 7 Scientific Advisory Board members, Daniele Wikoff of ToxStrategies (Scientific Review Team), Alison Kretser of IAFNS (Oversight Committee) Overall Conclusions - presented by Daniele Wikoff
Full session playlist  CoffeeBambooSmall

See IAFNS's other sessions at Experimental Biology 2017:

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Saturday, 22 April 2017
8:30AM - 12:30PM
Ballroom S100BC
Speakers: Dennis Keefe, FDA; Harris Lieberman, USARIEM; Esther Myers, EF Myers Consulting; Charles O'Brien, University of Pennsylvania; Jennifer Peck, University of Oklahoma; Milton Tenenbein, University of Manitoba; Connie Weaver, Purdue University; Daniele Wikoff, ToxStrategies
Supported by the Caffeine Working Group
Session Info & Videos The Changing Brain: How Brain Plasticity, Exercise and Nutrition Affect Function and Cognition
Saturday, 22 April 2017
3:00PM - 5:00PM,
Ballroom S100BC
  • Neurogensis and brain plasticity in the adult brain - Henriette van Praag, National Institute on Aging;
  • The Relation of Exercise, fitness, & Adiposity to Cognitive and Brain Health - Charles Hillman, University of Illinois - Video
  • Neuroinflammatory Processes in Cognitive Disorders - Sophie Laye, Universite Bordeaux - Video
  • Exercise, Nutrition and Brain Funciton: What are the steps toward dietary and physical activity Recommendations? - Mary Ann Johnson, University of Georgia - Video
  • Panel Discussion - Video
Utility of Predictive Modeling for Nutrition Research, Clinical Interventions and Public Health
Sunday, 23 April 2017
8:30AM- 10:30AM
S105BCD
Speakers:
  • Intro to Predictive Modeling: From Linear Regression Models to Mechanistic Mathematical Modeling - David Allison, University of Alabama at Birmingham - Video;
  • Use of Predictive Modeling in the Design of Clinical Studies Kevin Hall, NIDDK - Video;
  • Application of Predictive Modeling in Weight Loss Counseling -  Corby Martin, Pennington Biomedical Research Center - Video;
  • Application of Predictive Modeling in Personalized Nutrition - Ben van Ommen, TNO - Video;
  • Utility of PRedictive Modeling for Public Health Obesity Policies - Emily Dhurandhar, Texas Tech University - Video;
  • Summary and Wrap-Up - Diana Thomas, West Point - Video
    Supported by the Protein Committee
  • Full session playlist
Learning Lab: How to Access and Use a Fiber and Health Outcomes Database for Researchers and Policymakers
Tuesday, 25 April 2017
11:00AM - 12:30PM
S105AB
Speakers: Kara Livingston, Tufts University; Caleigh Sawicki, Tufts University
Supported by the Carbohydrate Committee Posters
Sources of dietary folate/folic acid in women of different races in the United States between 2009 and 2012: What is the role of fortified and enriched products?
PDF
Abstract Number: 6707
Poster Board Number C88
Presenter: Ray DeVirgiliis, George Washington University
Monday, 24 April
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Co-hosted by U.S. Food and Drug Administration, Center for Food Safety & Applied Nutrition (CFSAN) and the IAFNS Technical Committee on Food & Chemical Safety

This workshop will bring together scientists from government, academia and industry to discuss the advances in testing strategies to reduce animal testing and the need for the development of a standardized approach for use of these alternative methodologies in food safety assessment.

Workshop Proceedings:

State of the Science on Alternatives to Animal Testing and Integration of Testing Strategies for Food Safety Assessments

Read the Proceedings Registration Expand

There is no fee to attend the workshop but, registration is required by Tuesday, February 21. Please register for the workshop using this link: Workshop Registration

Webcast Registration
Register for webcast here: webcast registration
Webcast participants can submit questions online during the event. These will be answered as time allows. Agenda Expand

8:30-8:40 am: Welcome Suzanne Fitzpatrick, FDA Mansi Krishan, IAFNS

8:40-8:55am
Introductory Remarks
Dennis Keefe, FDA
Heidi Bialk, IAFNS Member Scientist 8:55-9:35am
Integrated Testing Strategies in Food Safety
Alan Boobis, Imperial College London [30 mins + 10 mins Q & A] 9:35-10:15am
State of the Science on High Through-Put Screening (HTS): Food Safety Perspective
Nadine Bewry, FDA 10:30-11:10am
Case Studies to Describe the Limitations of Using HTS data in Food Safety Assessment
Rebecca Clewell, ScitoVation 11:10 -11:50am
Identify and Translate Learnings from On-Going Assay Validation Efforts into Standard HTS Testing Practices
Richard Judson, EPA 12:50- 1:30pm
Read Across Approaches: Chemical Structure and Bioactivity Profiling Applicable to Food Safety
Grace Patlewicz, EPA 1:30-2:10pm
FDA Perspective on Read Across Approaches
Tim Adams, FDA 2:10-2:50 pm
Organ on a Chip Technology
Daniel Levner, Emulate 3:05- 4:30pm
Panel Discussion Moderator: Suzanne Fitzpatrick, FDA Panelists:
All speakers, Thomas Hartung, Johns Hopkins University and Katya Tsaioun, Johns Hopkins University 4:30-4:40pm
Concluding Remarks
Suzanne Fitzpatrick
FDA Mansi Krishan, IAFNS Videos Expand

A video of the workshop can be found on the FDA YouTube channel

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While the role of systematic reviews becomes more fully appreciated, the quality of systematic reviews is inconsistent. As the field of systematic reviews evolves, there are an increasing number of frameworks and approaches that can be used to conduct such comprehensive research.  When conducting systematic reviews there are questions about how to: develop a protocol and PICO (Population, Intervention, Comparator, Outcome) questions, execute a search strategy, manage data, grade the literature, evaluate and manage biases, and ensure transparency of the process. This session will address these components by using a large multi-endpoint systematic review of caffeine which followed the framework of the IOM Report "Finding What Works in Health Care: Standards for Systematic Reviews", as a case study.

There continues to be interest within the scientific community in what is a safe level of caffeine intake and if certain populations should have modified recommendations.  Since the 2003 release of the highly cited and valued review by Nawrot et al., "Effects of caffeine on human health", there have been more than 5,000 articles on the effects of caffeine in humans published, highlighting the need for an update to this body of work.

The Systematic Review of the effects of caffeine on human health took into account the challenges of including nutrition and toxicological evidence. The health endpoints reviewed for caffeine are: acute toxicity, behavior, bone and calcium homeostasis, cardiovascular health, developmental and reproductive toxicity, and pharmacokinetics in three healthy populations.  The session will present the lessons learned and will emphasize the efforts taken to ensure transparency and rigor that allow for the achievement of a high level of scientific quality.  Specific areas of focus will include challenges with identifying and integrating caffeine intakes by level of adversity (e.g., physiological or clinical endpoints), and difficulties in applying standard risk of bias tools across outcomes and endpoints.

Although this session will focus on the Caffeine Systematic Review as a case study, the process, findings, and lessons are relevant to nutrition researchers and professionals who utilize systematic reviews.

Agenda & Videos Expand Welcome
Alison Kretser, MS, RD, IAFNS The Caffeine Landscape - framing the need for the Systematic Review 
Dennis Keefe, PhD, FDA
Video Striving for the Gold Standard in the Systematic Review Process
Esther Myers, PhD, RDN, FAND, EF Myers Consulting
Video The Methodology and Challenges of the Caffeine Systematic Review
Daniele Wikoff, PhD, ToxStrategies
Video Q&A
Moderated by Dennis Keefe, PhD
Video

10:10 - 10:25 Break

General Results of the Systematic Review
Daniele Wikoff, PhD, ToxStrategies
Video

Results of Specific Health Endpoints- Scientific Advisory Board Members

  • Harris Lieberman, US Army - Behavior - Video 
  • Charles O'Brien, University of Pennsylvania - Behavior - Video (See Lieberman for pdf)
  • Jennifer Peck, PhD University of Oklahoma - Reproductive & Developmental Toxicity - Video 
  • Daniele Wikoff on behalf of Jeffrey Goldberger, University of Miami, Miller School of Medicine- Cardiovascular - Video 
  • Connie Weaver, PhD, Purdue University - Bone & Calcium - Video 
  • Milton Tenenbein, MD, University of Manitoba - Acute & Pharmacokinetics - Video 
Panel Discussion with the Caffeine Systematic Review Project Team Members Video
Moderated by Dennis Keefe, PhD
Panel includes: 6 of the 7 Scientific Advisory Board members, Daniele Wikoff of ToxStrategies (Scientific Review Team), Alison Kretser of IAFNS (Oversight Committee) Overall Conclusions - presented by Daniele Wikoff
Full session playlist  CoffeeBambooSmall

See IAFNS's other sessions at Experimental Biology 2017:

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2023

What’s In Food? How USDA’s FoodData Central and the Global Branded Food Products Database Supports Nutrition Research

Virtual, Event

The USDA Global Branded Food Products Database (GBFPD) is a component of USDA’s FoodData Central and the Public-Private Partnership between USDA, IAFNS, GS1 US, 1WorldSync, NielsenIQ Label Insight and the University of Maryland.

Read more about What’s In Food? How USDA’s FoodData Central and the Global Branded Food Products Database Supports Nutrition Research

Optimizing Cognitive Function with Foods, Nutrients, and Dietary Patterns: The Science and the Translation

Virtual, Event

The 2020 Dietary Guidelines Advisory Committee (DGAC) addressed several questions related to neurocognition, but was faced with “considerable variation in testing methods, inconsistent validity and reliability of cognitive testing methods, and differences between dietary patterns and cognitive outcomes examined,” precluding the ability to develop dietary recommendations. This webinar will focus on the science and translation of optimizing cognitive function with food.

Read more about Optimizing Cognitive Function with Foods, Nutrients, and Dietary Patterns: The Science and the Translation

IAFNS at IAFP 2023

Toronto, Canada

Each year, the International Association for Food Protection hosts an Annual Meeting, providing attendees with information on current and emerging food safety issues, the latest science, innovative solutions to new and recurring problems, and the opportunity to network with thousands of food safety professionals from around the globe. IAFNS is proud to support four sessions this year!

Read more about IAFNS at IAFP 2023

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IAFNS participated in the American Society for Nutrition Annual meeting - NUTRITION 2023 - presenting new work on funded projects.

Are We Ready? Resilience as a Biomarker for a "Healthy" Gut Microbiome Expand

Monday, July 24, 2023

2:00-3:30 pm ET

In partnership with the Nutritional Microbiology GEM and the International Scientific Association for Probiotics and Prebiotics

Chair: J. Phil Karl, PhD, RD, USARIEM

Speakers:

Curtis Huttenhower, PhD
Harvard T.H. Chan School of Public Health Abigail Johnson, PhD, RD
School of Public Health
University of Minnesota Jotham Suez, PhD
Johns Hopkins Bloomberg School of Public Health

Supported by: IAFNS Gut Microbiome Committee

It's Time to Quantify Intake Recommendations for Dietary Bioactives Expand

Sunday, July 23, 2023

8:00-9:30 a.m. E.T.

In partnership with the Research Interest Section on Bioactives

Chairs:

Johanna Dwyer, DSc, RD
Tufts University School of Medicine Charlene Van Buiten, PhD
Food Science and Human Nutrition
Colorado State University Speakers:
It is time to translate research evidence into quantified dietary bioactive intakes
John Erdman, Jr., PhD
University of Illinois at Urbana-Champaign Flavan-3-ols evidence translated into a quantified guideline
Gunter Kuhnle, PhD
University of Reading
Reading, England, United Kingdom It's time to quantify lutein intakes to support normal vision
Paul Bernstein, MD, PhD
University of Utah It's time to quantify omega-3 intakes to support normal pregnancy term
Susan Carlson, PhD
University of Kansas Medical Center Panel on next steps to communicate recommended intakes through health care providers.
Speakers and Julie Poteet, OD MS CNS FONS, Ocular Wellness and Nutrition Society

A collaboration with the IAFNS Lipids Committee and Bioactives Committee

For more information, see here.

USDA Global Branded Food Products Database Part of session: "Public Data Sharing - New Norms, Current State of Affairs, and Best Practices Going Forward" Expand

Tuesday, July 25, 2023

8:30-9:30 a.m. E.T.

Supported by: USDA Global Branded Food Products Database Partners

Presenters:

Kyle McKillop, MS, USDA-ARS

Alanna Moshfegh, MS, RD, USDA-ARS

For more information, see here.

Sodium Contributions of Categories of Food Obtained from Restaurants and Stores, Estimated by Considering Foods in Their As-Eaten Form: NHANES, 2009-2018 Expand

Poster Number: P14-041-23

Sunday, July 23, 2023

12:45-1:45 p.m. E.T.

Presenters:

Debra R. Keast, PhD, Food and Nutrition Database Research

Patricia Guenther, PhD, RD, Guenther Consulting

Supported by: IAFNS Sodium Committee

For more information, see here.

The Broader Dietary Value and Consequences of Top Food Categories of Sodium Intake Expand

Poster Number: P24-001-23

Monday, July 24, 2023

11:45 a.m. - 12:45 p.m. E.T.

Presenter: Mavra Ahmed, PhD, University of Toronto

Co-authors:

Anthea Christoforou, PhD
University of Toronto Mary R. L'Abbe, PhD
University of Toronto Christine Mulligan, BSc
University of Toronto Alena P. Ng, Msc.
University of Toronto

Supported by: IAFNS Sodium Committee

For more information, see here.

An Overview of Reviews on the Association of Low-Calorie Sweetener Consumption With Body Weight and Adiposity Expand

Poster Number: P31-025-23

Monday, July 24, 2023

12:45-1:45 p.m. E.T.

Presenter: Kelly Higgins, PhD, MPH, USDA ARS

Co-authors:

Rita Rawal, PhD, RD
USDA-ARS Matthew Kramer
USDA-ARS (retired) David J. Baer, PhD
USDA-ARS David Klurfeld, PhD
Indiana University,
School of Public Health-Bloomington

Supported by: IAFNS Low- and No-Calorie Sweetener Committee.

For more information, see here.

 

Low-Carbohydrate Dietary Patterns are Associated with Beneficial Long-term Changes in Systemic Markers of Inflammation in the Framingham Offspring Cohort Expand

Poster Number: P29-002-23

Monday, July 24, 2023

11:45 a.m. - 12:45 p.m. E.T.

Presenter: Ghaida Aloraini, Tufts University

Co-authors:

Nicola M. McKeown, PhD
Boston University Alice H. Lichtenstein, DSc
JM USDA Human Nutrition Research Center on Aging, Tufts University Sai Krupa K. Das, PhD
JM USDA Human Nutrition Research Center on Aging, Tufts University Paul F. Jacques, DSc
Tufts University

Supported by: IAFNS Lipids Committee

For more information, see here.

 

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Join IAFNS at the IAFP 2023 Annual Meeting July 16-19, 2023 in Toronto, Ontario, Canada: https://www.foodprotection.org/annualmeeting/

Genomics in Food Safety- How to Use the Tools to Prevent Outbreaks Expand

Convenor: Heather Carleton, CDC

Speakers:

  • Martin Wiedmann, Cornell University
  • Yan Luo, FDA
  • Jessie Heidenreich, Hilmar Cheese Company

Date and Time: Monday, July 17, 2023 from 10:45AM-12:15PM

Event Link: https://iafp.confex.com/iafp/2023/onlineprogram.cgi/Session/8847

Data Sharing in the Digital Age of Food Safety Expand

Convenor: Kathy Glass, University of Wisconsin

Panelist:

  • De Ann Davis, Western Growers Association
  • Angie Siemens, Cargill
  • Sophia Santillana-Farakos, FDA
  • James Doyle, Crème Global
  • Marie Breton, Health Canada

Date and Time: Monday, July, 17, 2023 from 3:45 to 5:15 PM

Event Link: https://iafp.confex.com/iafp/2023/onlineprogram.cgi/Session/8849

Investigating Ambiguous Outbreaks and Adverse Events Expand

Convenor: Laurie Post (Deibel Labs) and Kelly Dawson (Conagra Brands)

Speakers:

  • Craig Hedberg, University of Minnesota
  • Tim Jackson, FDA
  • Michael Vasser, CDC
  • Mitzi Baum, STOP Foodborne Illness

Date and Time: Wednesday, July 19, 2023 from 1:30-3:30 PM

Event Link: https://iafp.confex.com/iafp/2023/onlineprogram.cgi/Session/8835

From Farm to Food: A New Perspective on Heavy Metals in Human Diets Expand Convenor: Paul Hanlon, Abbott Nutrition Speakers:
  • Benjamin Runkle, University of Arkansas
  • Felicia Wu, Michigan State University
  • Kevin Boyd, The Hershey Company
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